|Title||Associate Professor, Department of Colorectal Surgery|
Dr. Chen is experienced in surgical treatment for abdominal tumors, specially for gastrointestinal tumor and colostomy.
Colorectal Cancer Treatment
1998 Graduated from Sun Yat-Sen University
2001 – 2003 Fellowship Trainee, the University of Adelaide and the Queen Elizabeth Hospital, Australia
2003 PhD in Medicine
Last updated on: May, 2014
|Title||Attending professor, associate chief physician, advisor of master’s degree student|
Dr. Wu Xiaojun, MD of Clinical Oncology, is an attending professor and associate chief physician for Department of Colorectal Surgery at Sun Yat-sen University Cancer Center. He graduated from the Department of Clinical Medicine in former Sun Yat-sen University of Medical Sciences in 1996.
Currently he is engaged in the diagnosis and treatment of gastroenteric tumor and specializes in combination therapy for colorectal cancer, diagnosis and treatment of gastrointestinal stromal tumor as well as the prevention and treatment of community oncology. Meanwhile he is the member of the Guangdong Standing Committee of Colorectal Cancer CACA, member of Colorectal and Anal Surgery Branch of Guangdong Medical Association and member of the Standing Committee of Tumor Prevention and Treatment, Guangdong Health Management Association. After graduation, he headed for Yunnan Provincial People's Hospital to support the construction of the border areas by dedicating himself to surgical oncology. In 2006, appointed by Department of Health of Guangdong Province and Sun Yat-sen University Cancer Center, Dr. Wu Xiaojun got involved in the medical support program of Guangdong “Health Talent Support for Mountain Area” and served as the Vice President of Zijin County People's Hospital of Heyuan to take charge of medical treatment, scientific research and teaching.
By 2014, he has presided over and participated in 12 research projects and 4 global clinical trials, mainly centered on research work related to liver metastasis of colorectal cancer, chemoradiotherapy sensitivity, prognosis of immunologic function and curative effect as well as gastrointestinal stromal tumor. He has composed and published 65 papers, including 20 SCI papers, and edited 7 monographs, such as Book Series of Community Prevention and Treatment of Tumors -- Diet and Cancer, Community Oncology, Colorectal Cancer, Stoma Therapy and Rehabilitation - Theory and Practice, Colorectal Carcinoma, Modern Clinical Nursing Practice of Wound and Stoma and Medical Oncology. The project he partook in, Application Research of Community Prevention and Comprehensive Treatment for Colorectal Cancer, won the second Science and Technology Award of Chinese Anti-Cancer Association and the second Prize for Progress in Science and Technology of Guangdong Province. Additionally, Dr. Wu Xiaojun serves as the physician of medical evaluation for Glivec International Patient Assistance Program (GIPAP) and Cancer Foundation of China SPAP (Sutent Patient Assistance Program).
Combination therapy for colorectal cancer, diagnosis and treatment of gastrointestinal stromal tumor as well as the prevention and treatment of community oncology
1991-1996 Department of Clinical Medicine in former Sun Yat-sen University of Medical Sciences 1996-2000 Department of Surgical Oncology in Yunnan Provincial People's Hospital 2000-2003 Master’s degree student of Oncology in Zhongshan School of Medicine, SYSU2003-2012 Worked in Sun Yat-sen University Cancer Center (2007-2010 doctoral student of Oncology)2006 Supported Zijin County People's Hospital of Guangdong, served as Vice President, and took charge of clinical work, teaching and scientific research2009 Served as Secretary of Colorectal Surgery 2012 Attended the short-term training in MGH, the United States
1. Hospital-based colorectal cancer survival trend of different tumor locations from 1960s to 2000s. PLoS One. 2013 Sept. 12;8(9).
2. Study on associated biomarkers influencing recurrence, metastasis and prognosis in patients with gastrointestinal stromal tumors after complete resection. Chinese Journal of Gastrointestinal Surgery. 2013 Mar;16(3):242-6.
3. Celecoxib can prevent capecitabine-related hand-foot syndrome in stage II and III colorectal cancer patients: result of a single-center, prospective randomized phase III trial. Ann Oncol. 2012 May;23(5):1348-53.
4. Circulating antibodies to carcinoembryonic antigen related to improved recurrence-free survival of patients with colorectal carcinoma. J Int Med Res. 2011;39(3):838-845.
5. The effect of COX-2 inhibitor on capecitabine-induced hand-foot syndrome in patients with stage II/III colorectal cancer: a phase II randomized prospective study. J Cancer Res Clin Oncol. 2011 Jun;137(6):953-957.
6. The prognostic significance of peripheral T-lymphocyte subsets and NK cells in patients with colorectal cancer. Hepato-Gastroenterology. 2009 Oct.56:1310-1315.
7. Prognostic factors in surgically managed gastrointestinal stromal tumors. J Int Med Res. 2012;40(5):1904-11.
8. Surgical treatment for 140 patients with gastric stromal tumors. Chinese Journal of Gastrointestinal Surgery. 2010 Jun;13(6):417-20.
Last updated on: 2013
|Title||Associate Professor and Deputy Director of Colorectal Department|
Dr. Li-ren Li is associate professor and deputy director of colorectal department of Sun Yat-sen University Cancer Center. Dr. Li obtained his Bachelor in Medicine (equivalent to MD in the US) and PhD at Sun Yat-sen University of Medical Sciences, P. R. China in 1998 and 2005, respectively. He received surgical training at Queen Elizabeth Hospital of University of Adelaide, Australia from 2003 to 2004, learning laparoscopic colorectal resection. He was appointed as associate professor in 2007 and deputy director of colorectal department in 2009. He worked as a visiting scientist at Harvard medical school Dana-Farber cancer institute and University of Texas MD Anderson Cancer Center under the supervision of Prof. Ronald Depinho and Prof. Lynda Chin from 2010 to 2013, offering him with great opportunities to explore the fields of tumorigenesis, tumor metabolism, tumor metastasis, and drug resistance of tumor cells. He rejoined Sun Yat-sen University Cancer Center at the end of 2013, and focuses on multiple disciplinary therapy model of colorectal cancer and molecular mechanism of tumor metastasis. Dr. Li has published more than 20 research papers.
Multiple disciplinary therapy model of colorectal cancer and molecular mechanism of tumor metastasis.
M.S. in Surgery
M.D., Ph.D. in Oncology
1. Ian R. Watson, Liren Li, Peter K. Cabeceiras, et al. The RAC1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of RAF. Cancer Research, 2014 (accepted).
2. Wang G, Gao Y, Li L, Jin G, Cai Z, Chao JI, Lin HK. K63-linked ubiquitination in kinase activation and cancer. Front Oncol. 31, 2(5): 1-13, 2012.
3. Ding Z, Wu CJ, Jaskelioff M, Ivanova E, Kost-Alimova M, Protopopov A,Chu GC, Wang G, Lu X, Labrot ES, Hu J, Wang W, Xiao Y, Zhang H, Zhang J, Zhang J, Gan B, Perry SR, Jiang S, Li L, Horner JW, Wang YA, Chin L, DePinho RA. Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases. Cell. 148(5): 896-907, 2012.
4. Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, Voet D, Saksena G, Stransky N, Onofrio RC, Winckler W, Ardlie K,Wagle N, Wargo J, Chong K, Morton DL, Stemke-Hale K, Chen G, Noble M, Meyerson M,Ladbury JE, Davies MA, Gershenwald JE, Wagner SN, Hoon DS, Schadendorf D, Lander ES, Gabriel SB, Getz G, Garraway LA, Chin L. A landscape of driver mutations in melanoma. Cell. 150(2):251-63, 2012.
5. Comprehensive molecular characterization of human colon and rectal cancer. Nature. 487(7407):330-7, 2012.
6. Li LR;Fang YJ;Pan ZZ;Wu XJ;Wan DS;Hardingham JE;Rieger N. Length of lymphangiogenesis in the rectal tissues distal to rectal cancer. Tumour Biol. 31(6): 667-71, 2010.
7. Fang YJ;Pan ZZ;Li LR;Lu ZH;Zhang LY;Wan DS. MMP7 expression regulated by endocrine therapy in ERbeta-positive colon cancer cells. Journal of experimental & clinical cancer research, 2009, 28: 132.
8. Li LR, Wan DS, Pan ZZ, et al. Expression of hTERT in activated lymphocytes using real-time RT-PCR. Journal of Colorectal & Anal Surgery, 2007: 7-10.
9. Li LR, Wan DS, Pan ZZ, et al. Prognostic effect of lymphatic spreading of colorectal cancer.GuangdongProvinceJournal of Medicine, 2006: 1819-1821.
10. Li LR, Wan DS, Pan ZZ, et al. Predictive mathematical model for lymphatic metastasis of colorectal cancer. Bulletin of Chinese Cancer, 2006: 876-878.
11. Li LR, Wan DS, Pan ZZ, et al. Effect of clinicopathologic parameters on lymphatic metastasis of colorectal cancer.ChinaTropical Medicine, 2006:1160-1163.
12. Li LR, Wan DS, Pan ZZ, et al. Clinical feature and treatment strategy of anal canal adenocarcinoma. Chinese Journal of Gastrointestinal Surgery, 2006: 402-404.
13. Li LR, Wan DS. Advance in lymphangiogenesis of colorectal cancer, 2006: 382-384.
14. Li LR, Wan DS, Pan ZZ, et al. Relationship between VEGFR-3 and Prox1 incolorecal cancer.GuangdongProvinceJournal of Medicine, 2005: 1488-1490.
15. Li LR, Pan ZZ, Nick Rieger, et al. Clinical significance of expression of hTERT in colorectal cancer. Aizheng, 2004: 1502-1507.
16. Li LR, Huang YH. Comparison between tension-free inguinal hernia repair and Bassini repair. Chinese Journal of General Surgery, 2001: 47-49.
1. Li LR, Wan DS. Appendix adenoma and carcinoid. Colorectal Cancer, Peking: Chinese Medical Science Publishing House, 2004.
2. Li LR, Wan DS. Large bowel perforation. Stoma rehabilitation and treatment: theory and practice, Peking: Chinese Medical Science Publishing House, 2006.
3. Li LR, Wan DS.Melanoma in anorectum. Colorectal cancer, Peking: Peking University MedicalPress, 2008.
Last updated on: July, 2014
|Title||Associate Professor, Department of Colorectal Surgery|
Dr. Peirong Ding has extensive experience and expertise in developing treatment for Colorectal Cancer, Gastrointestinal Stromal Tumor and Gastrointestinal Neuroendocrine Tumor, especially in anal endoscopic microsurgery (TEM) for colorectal cancer in early stage, anus surgery for rectal cancer, treatment for colorectal cancer liver metastasis, and chemotherapy treatment for metastatic colorectal cancer.2011- Present Associate Professor, Department of Colorectal Surgery, Sun Yat-Sen University Cancer Center2008 - 2010 Lecturer, Department of Abdomen, Sun Yat-Sen University Cancer Center2002 - 2007 Residency Doctor, Department of Abdomen, Sun Yat-Sen University Cancer Center
1997 - 2002 MB, Sun Yat-Sen University
2005 – 2010 PhD in Medicine, Sun Yat-Sen University
2009 - 2010 Visiting Scholar, Memorial Sloan Kettering Cancer Center, the United States
Last updated on: May, 2014