Research
    Zhou Fangjian
    Title Professor, Director of the Department of Urology
    Profile

    Modified radical cystectomy
    Our group has made several modifications to the traditional radical cystectomy. The first is a modified technique to prevent complications related to stoma and ileoureteral anastomosis in patients undergoing ileal conduit diversion. The second is a modified technique for neourethral anastomosis in orthotopic neobladder reconstruction. Both of the two modifications have been widely accepted by peers.

    Nephron sparing operation
    Our group pays a lot of attention to nephron sparing operation. As more and more small renal mass being detected accidentally by body exam, and the prolonged  life span, preserving the kidney is more and more important. Our group made some modification to the traditional nephron sparing operation, which significantly reduced the postoperative complication.

    The mechanisms of Bladder cancer metastasis
    Metastasis is the main reason of failure in cancer treatment. Bladder cancer with metastasis is incurable. Hence exploring the mechanisms of Bladder cancer metastasis can provide new idea in the treatment of bladder cancer. Our group demonstrated that up-regulation of Nkx2.8 inhibited epithelial-mesenchymal transition (EMT), an early key event in cancer metastasis, in bladder cancer cells. The research is supported by the grants from the Natural Science Foundation of China (No. 81272810) and the Natural Science Foundation of Guangdong Province, China(No. S2012010009466).

    1995, The first award for“The series studies of renal stone and renal function” Hunan Province Science and Technology Association

    Email zhoufj@sysucc.org.cn
    Phone
    Research Interest(s)

     

    Education

    Obtained Medical Bachelor in 1984, Medical Master in 1987 and Medical Doctor in 1992  from Hunan Medical University

    Publications

    1. Zhang Z, Li J, Zheng H, Yu C, Chen J, Liu Z, Li M, Zeng M, Zhou F, Song L. Expression and cytoplasmic      localization of SAM68 Is a significant and independent prognostic marker for renal cell carcinoma. Cancer Epidemiol  Biomarkers Prev. 2009,18:2685-93

    2. Guo-Liang Hou , Yong-Hong Li , Zhi-Ling Zhang , Yong-Hong Xiong , Xiao-Feng Chen , Kai Yao, Zhuo-Wei Liu , Hui Han , Zi-Ke Qin , Fang-Jian Zhou. A modified technique for neo-urethral anastomosis in orthotopic neobladder reconstruction. Urology. 2009,74:1145-1149

    3. Kai Yao, Guo-Liang Hou., Zhuo-Wei Liu , Shao-Long Yu, Yong-Hong Li, Fang-jian Zhou. Upper urinary tract dilation due to conglutination of intraluminal distal ureters after orthotopic neobladder with split-cuff nipple ureteral reimplants: Early results of 8 cases. Urologic Oncology: Seminars and Original Investigations,2009, 27: 611–616

    4. Zhou J, Weng D, Zhou F, Pan K, Song H, Wang Q, Wang H, Wang H, Li Y, Huang L, Zhang H, Huang W, Xia J. Patient-derived renal cell carcinoma cells fused with allogeneic dendritic cells elicit anti-tumor activity: in vitro results and clinical responses. Cancer Immunol Immunother. 2009, 58(10):1587-97. (IF: 3.804)

    5. Zi-Ke Qin, Jian-An Yang, Yun-lin Ye, Xing Zhang, Li-Hua Xu, Fang-Jian Zhou, Hui Han, Zuo-Wei Liu, Li-Bing Song and Mu-Sheng Zeng. Expression of Bmi-1 is a prognostic marker in bladder cancer. BMC Cancer 2009, 9:61

    6. Fang J. Zhou, Shao L. Yu, Yong H.Li, Zhuo W. Liu, Yong H. Xiong, Pei H. Wu, Hui Han, Zi K.Qin. Intra-arterial chemotherapy with gecitabine and cisplatin for patients with recurrence of transitional cell carcinoma confined to the pelvis. J Chemo, 2009, 21(1):91-97 

    7. Wei Chen, Jun-hang Luo, Wen-feng Hua, Fang-jian Zhou, Marie C. Lin, Hsiang-fu Kung, Yi-xin Zeng, Xin-yuan Guan, Dan Xie. Overexpression of EIF-5A2 is an independent predictor of outcome in patients of urothelial cancer of the bladder treated with radical cystectomy. Cancer Epidemiol Biomakers Prev 2009,18(2):400-4008

    8. Dong P, Flores J, Pelton K, Solomon KR. Prohibitin is a cholesterol-sensitive regulator of cell cycle transit.J Cell Biochem. 2010,111(5):1367-74.

    9. Kai Yao, Hua Tu, Yong-Hong Li, Zi-Ke Qin, Zhuo-Wei Liu, Fang-Jian Zhou, Hui Han. Modified technique of radical inguinal lymphadenectomy for penile carcinoma: morbidity and outcome.J Urol. 2010, 184:546-552

    10. Yong-Hong Xiong, Zhi-Ling Zhang, Yong-Hong Li,Zhuo-Wei Liu, Guo-Liang Hou,Qing Liu,Jing-Ping Yun, Xue-Qi Zhang and Fang-Jian Zhou. Benign pathological findings in 303 Chinese patients undergoing surgery for presumed localized renal cell carcinoma. Int J Urol, 2010,17:517-521

    11. Zhi Ling Zhang, Zhuo Wei Liu, Fang Jian Zhou, Yong Hong Li, Yong Hong Xiong, Kai Rao, Guo Liang Hou, Hui Han, Zi Ke Qin, Shao Long Yu, Xiao Feng Chen. Modified technique to prevent complications related to stoma and ileoureteral anastomosis in patients undergoing ileal conduit diversion.Urology,2010,76(4): 996-1000

    12. Jun-Hang Luo, Fang-Jian Zhou, Dan Xie, Zhi-Ling Zhang, Bing Liao, Hong-Wei Zhao, Yu-Ping Dai, Ling-Wu Chen, Wei Chen. Analysis of long-term survival in patients with localized renal cell carcinoma: laparoscopic versus open radical nephrectomy. World J Urol, 2010,28: 289

    13. Zhang Zhi-ling, Xiong Yong-hong, Li Yong-hong, Hou Guo-liang, Liu Zhuo-wei, Han Hui, Qin Ze-ke,Yun Jing-ping, Zhou Fang-jian. Reassessment of the predictive role of perivesical fat invasion in invasive bladder cancer prognosis in 151 chinese patients. Chinese Medical J, 2011:124(18):2915-2919

    14. Song Wu, Yong Wang, Liang Sun, Zhiling Zhang, Zhimao Jiang, Zike Qin, Hui Han, Zhuowei Liu, Xianxin Li, Aifa Tang, Yaoting Gui, Zhiming Cai and Fangjian Zhou.  Decreased expression of dual-specificity phosphatase 9 is associated with poor prognosis in clear cell renal cell carcinoma. BMC Cancer, 2011, 11:413

    15. Liu ZW, Zhang XQ, Hou GL, Zhang ZL, Qin ZK, Han H, Zhou FJ. Primary adult intratesticular rhabdomyosarcoma: Results of the treatment of six cases. Int J Urol. 2011,18(2):171-4.

    16. Yun-Lin Ye, Xiang-Zhou Sun, Fu-Fu Zheng, Jun Bian, Yan-Ping Huang, Xue-Qi Zhang, Zhi-Xun Li, Ying Nie, Zi-Ke Qin, and Yu-Ping Dai. Clinical Analysis of Management of Pediatric Testicular Germ Cell Tumors. Urology.2012,56(1):112-118

    17. Kai Yao,Hyewon Youn,Xiaoyan Gao,Bijun Huang,Fangjian Zhou, Benyi Li, and Hui Han*.Casein Kinase 2 Inhibition Attenuates Androgen Receptor Function and Cell Proliferation in PC Cells. The Prostate,2012. Published online

    18. Zhuo-Wei Liu,Ephrem O.Olweny,Gang Yin,Stephen Faddegon,Yung K.Tan, Woong  Kyu Han,Jeffrey A. Cadeddu. Prediction of perioperative outcomes following minimally invasive partial nephrectomy: role of the R.E.N.A.L nephrometry score. World J Urol,2012,DOI:10.1007/s00345-012-0876-3O

    19. Chen Ming-Kun,YE Yun-lin,ZHOU Fang-jian,LIU Jian-ye,LU Ke-shi,HAN Hui,LIU Zhuo-wei,XU Zhen-zhou and QIN Zi-ke. Clipping Extremity of Ureter Is Effective for Preventing Bladder Recurrence after Upper Urinary Tract Urothelial Carcinoma,Chinese Medical Journal. 2012.125(21):3821-3825

    20. Chen Ming-Kun,YE Yun-lin, ZHOU Fang-jian,LIU Jian-ye,LU Ke-shi,HAN Hui,LIU Zhuo-wei,XU Zhen-zhou and QIN Zi-ke. Clipping Extremity of Ureter Is Effective for Preventing Bladder Recurrence after Upper Urinary Tract Urothelial Carcinoma,Chinese Medical Journal. 2012,125(21):3821-3825

    21. Liu JY, Li YH, Lin HX, Liao YJ,Mai SJ, Liu ZW, Zhang ZL, Jiang LJ, Zhang JX, Kung HF, Zeng YX, Zhou FJ (Xie D  Overexpression of YAP 1 contributes to progressive features and poor prognosis of human urothelial carcinoma of the bladder. BMC Cancer. Epub 2013 Jul 19.

    22. Liu JY, Zhang Q, Ye YL, Li J, Chen W, Li YH, Zhang ZL, Yao K, Jiang LJ, Han H, Liu ZW, Qin ZK, Zhou FJ. Prognostic significance of tumor location and superficial urothelial bladder carcinoma history in patients with ureteral urothelial carcinoma treated with radical nephroureterectomy. 2013,45(2):395-404

    23. Kai Yao, Zai-Shang Li, Fang-Jian Zhou, Zi-Ke Qin, Zhuo-Wei Liu, Yong-Hong Li and Hui Han*. Anatomical retroperitoneoscopic retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell tumours: initial operative experience. Asian  J  Andrology, 2013,11

    24. Pei Dong,Zhou wei Liu,Xiang Dong Li,Yong Hong Li,Kai Yao,Song Wu,Zi Ke Qin,Hui Han,Fang jian Zhou. Risk factors for relapse in patients with clinical stage I testicular nonseminomatous germ cell tumors. Med Oncol,2013,30:494.

    Han Hui
    Title Professor and Deputy Director
    Profile

    Prof. Han is specialized in treating patients with genitourinary system cancers, including bladder, kidney, prostate,adrenal gland, ureter, urethra, testis, epididymis, spermatic cord, and penis and so on. He is good at various kinds of urological operations, especially retroperitoneal lymph node dissection and inguinal lymphadenectomy.

    Prof. Han perform laparscopic and open procedures to treat these cancers, often in a multi-disciplinary team approach with the integration of expertise by medical oncology and/or radiation oncology. He also pursued technical innovations which have transformed the management of these cancers including open inguinal lymphadenectomy, laparoscopic retroperitoneal lymph node dissection, open/ laparoscopic radical nephrectomy and laparoscopic radical prostatectomy.

    Annually, Prof. Han perform approximately 100 partial/radical nephrectomy procedures for kidney cancer, 20 prostatectomy procedures for prostate cancer, 20 cystectomy procedures for bladder cancer, 20 lymph node dissections for penile cancer, and 15 retroperitoneal lymph node dissections for testis cancer. He also has unique expertise in managing rare urologic cancers and salvage procedures for recurrent cancers of the bladder and prostate that have failed initial therapy with surgery or other treatments.

    Email hanhui@sysucc.org.cn
    Phone
    Research Interest(s)
    Education

    Prof. Han trained in the Tong Ji University School of Medicine. He acquired M.D in Tong Ji University School of Medicine  and completed his Residency training in Tong Ji hospital.

    Publications

    1.Kai Yao, Hyewon Youn, Xiaoyan Gao,Bijun Huang,Fangjian Zhou, Benyi Li and Hui Han*. Casein Kinase 2 Inhibition Attenuates Androgen Receptor Function and Cell Proliferation in PC Cells. The Prostate, 72 (4):1423-1430,  2012   (IF 4.14)

    2.Kai Yao, Zai-Shang Li, Fang-Jian Zhou, Zi-Ke Qin, Zhuo-Wei Liu, Yong-Hong Li, Hui Han*. Anatomical retroperitoneoscopic retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell tumors: initial operative experience, Asian Journal of Andrology ,16 (1):136-139,  2014   (IF 2.140)

    3.Kai Yao, Peng Chen, Zi-jun Zou, Zi-Ke Qin, Zhuo-Wei Liu , Yong-Hong Li, Fang-Jian Zhou, Hui Han*. Disease specific survival after radical lymphadenectomy for penile cancer: prediction by lymph node count and density. Urologic Oncology: Seminars and Original Investigations, 2013, Dec 30. [Epub ahead of print] (IF 3.647)

    4. Kai Yao, Zi-jun Zou, Zai-shang Li, Fang-Jian Zhou, Zi-Ke Qin, Zhuo-Wei Liu, Yong-Hong Li, Hui Han*. Fascia lata preservation during inguinal lymphadenectomy for penile cancer:rationale and outcome, Urology , 82 (8):642-647,  2013   (IF 2.424)

    5.Kai Yao,  Hua Tu, Yong-Hong Li, Fang-Jian1 Zhou and Hui Han*. Modified Technique of Radical Inguinal Lymphadenectomy for Penile Carcinoma: Morbidity and Outcome, Journal of Urology, 184(8):546-552, 2011   (IF 3.696)

    6.Han H*, Yao K, Zhou FJ. Modified Technique of radical inguinal lymphadenectomy to reduce the complication of skin necrosis for penile carcinoma, European Urology Supplements, 10(2): 339-340, 2011   (IF 2.162) 

    7.Han H*, Youn YH, Yao K, Zhou FJ, Huang HB, Li BY. CK2-selective CK2 inhibitor: effect on AR receptor and cell cycle in castrationresistant prostate cancer cell line, European Urology Supplements, 10 (2): 292-293, 2011    (IF 2.162) 

    8.Han H*, Yao K, Zhou FJ. Extroperitoneal lymph node dissection ( report of 7 cases). J of endourology .2008:22(supl 1):A286

    Qin Zike
    Title Professor, Chief Physician
    Profile Bladder cancer, kidney cancer, prostate cancer, testicular cancer, and other comprehensive treatment.
    Email qinzk@sysucc.org.cn
    Phone
    Research Interest(s) Principles of bladder cancer. In recent years, we investigated the role of  Bmi-1 in progression and metastasis of bladder cancer and found that Bmi-1 was related to recurrence and progression of  bladder cancer.
    Education 1984—1989  Guangxi Medical university, Bachelor Degree

    1993--1996  Cancer Center of Sun Yat-sen University, Master Degree

    1996--1999  First Affiliated Hospital of Sun Yat-sen University, Doctor Degree

    Publications 1. Intra-arterial Chemotherapy Is Reliable in Preventing High-risk Superficial Bladder Cancer from Recurrence and Progression. Journal of Chemotherapy. 2009,21(6): 681-686 .


    2. Expression of Bmi-1 is a Prognostic Marker in Bladder Cancer. BMC Cancer,2009, 9: 61-68 .

    3. Clipping the extremity of ureter prior to nephroureterectomy is effective for preventing subsequent bladder recurrence after upper urinary tract urothelial carcinoma. Chin Med J (Engl).125(21):3821-6,2012.

    4. Clinical Analysis of Management of Pediatric Testicular Germ Cell Tumors Urology.2012, 79(4): 892-7 .

    5. The risk factors for the presence of pelvic lymph node metastasis in penile squamous cell carcinoma patients with inguinal lymph node dissection. World J Urol.  2013,(6):1519-24.

    6. Intra-arterial chemotherapy with gemcitabine and cisplatin in locally advanced or recurrent squamous cell carcinoma of penis. Chinese Journal of Cancer.  2013,(11):619-23.

    Liu Zhuo-Wei
    Title Vice-President and Professor
    Profile

    As an oncological urologist, Dr. Liu specializes in the surgical treatment of urinary tumors, especially in robotic and minimally invasive laparoscopic surgeries, as well as the comprehensive treatment of bladder cancer and testicular cancer, and the surgical treatment of children's tumors. He is one of the first surgeons in China to carry out robot-assisted/laparoscopic retroperitoneal lymph node dissection for testicular cancer and ultra-expanded lymph node dissection for bladder cancer. He has been awarded the Outstanding Contribution Award for the Highest Volume of 3-4 level difficulty Surgeries as the chief professor of Sun Yat-sen University Cancer Center. He has undertaken more than 10 research projects with funding from the National Natural Science Foundation of China and the Guangdong Natural Science Foundation, and published more than 40 articles as the first author (corresponding author), participated in editing six academic works, and served as the deputy chief editor of Bladder Cancer.

    Email liuzhw@sysucc.org.cn
    Phone
    Research Interest(s)

    Minimally invasive surgery for Urological oncology.

    Multidisciplinary management for bladder cancer and testicular cancer

    Education

    1998-2000  Bachelor and Master Degree of Medicine, Medical School of Sun Yat-sen University, Guangzhou, China

    2003-2006  Doctoral Degree in Oncology, Sun Yat-sen University, Guangzhou, China

    Visiting scholar
    2004-2005  Department of Urology, Hokkaido University, Sapporo, Japan (Training for laparoscopic surgery)

    2011-2012  Department of Urology, UT Southwestern Medical Center, Dallas, United States, visiting assistant professor

    Publications

    1) Shengjie Guo, Zefu Liu, Xiangdong Li, Kai Yao, Pei Dong, Dong Chen, Chunxian Liao, Zhaolin Long, Yongqiang Wang, Fangjian Zhou, Xiaobo He, Zhuowei Liu, The prognostic value of the site of invasion in T3aN0M0 clear cell renal cell carcinoma, Urologic Oncology: Seminars and Original Investigations, Volume 37, Issue 5, 2019, Pages 301.e11-301.e17

    2) Li X, Dong P, Wei W, Jiang L, Guo S, Huang C, Liu Z, Chen J, Zhou F, Xie D, Liu Z. Overexpression of CEP72 Promotes Bladder Urothelial Carcinoma Cell Aggressiveness via Epigenetic CREB-Mediated Induction of SERPINE1. Am J Pathol. 2019 Jun;189(6):1284-1297.

    3) Li XD, Huang CW, Liu ZF, Jiang LJ, Chen JW, Xie D, Zhou FJ, Lu HM, Liu ZW. Prognostic Role of the Immunoscore for Patients with Urothelial Carcinoma of the Bladder Who Underwent Radical Cystectomy. Ann Surg Oncol 26, 4148–4156 (2019).

    4) Shao-Xu Wu, Jian Huang, Zhuowei Liu, Hai-Ge Chen, Pi Guo, Qing-Qing Cai, Jun-Jiong Zheng, Hai-De Qin, Zao-Song Zheng, Xin Chen, Rui-Yun Zhang, Si-Liang Chen, Tian-Xin Lin. A Genomic-clinicopathologic Nomogram for the Preoperative Prediction of Lymph Node Metastasis in Bladder Cancer. EBioMedicine, 2018, 54-65

    5) Yu C, Liu Z, Chen Q, Li Y, Jiang L, Zhang Z, Zhou F. Nkx2.8 Inhibits Epithelial-Mesenchymal Transition in Bladder Urothelial Carcinoma via Transcriptional Repression of Twist1. Cancer Res. 2018 Mar 1;78(5):1241-1252

    6) Zefu Liu, Shiyang Zheng, Xiangdong Li, Shengjie Guo, Yanjun Wang, Fangjian Zhou, Zhuo Wei Liu. Oncologic Outcomes of Patients Undergoing Diagnostic Ureteroscopy Before Radical Nephroureterectomy for Upper Urinary Tract Urothelial Carcinomas: A Systematic Review and Meta-Analysis. J Laparoendosc Adv Surg Tech A. 2018 Nov;28(11):1316-1325

    7) Liu Z, Ye Y, Li X, Guo S, Jiang L, Dong P, Li Y, Shi Y, Fan W, Cao Y, Yao K, Qin Z, Han H, Zhou F, Liu Z. The effects of intra-arterial chemotherapy on bladder preservation in patients with T1 stage bladder cancer. World J Urol. 2018 Aug;36(8):1191-1200.

    8) Li Z, Liu Z, Yao K, Qin Z, Han H, Li Y, Dong P, Ye Y, Wang Y, Wu Z, Zhang Z, Zhou F. Modified Ileal Conduit Has Fewer Complications Related to Stoma and Ureteroileal Anastomosis as Compared with Conventional Bricker. Cancer Commun (Lond). 2019 Apr 18;39(1):19.

    9) Li XD, Zhang JX, Jiang LJ, Wang FW, Liu LL, Liao YJ, Jin XH, Chen WH, Chen X, Guo SJ, Zhou FJ, Zeng YX, Guan XY, Liu ZW, Xie D. Overexpression of maelstrom promotes bladder urothelial carcinoma cell aggressiveness by epigenetically downregulating MTSS1 through DNMT3B. Oncogene. 2016 Dec 8;35(49):6281-6292.

    10) Li X, Guo S, Wu Z, Dong P, Li Y, Zhang Z, Yao K, Han H, Qin Z, Zhou F, Liu Z. Surveillance for patients with clinical stage I nonseminomatous testicular germ cell tumors. World J Urol. 2015 Sep;33(9):1351-7.

    11) Li Xiangdong,Guo Shengfie,Chen Siliang,Liu ZeFu,Dong Pei,Zhang Zhiling,Jiang Lijuan,Yao Kai,Li Yonghong,Hanhui,Qin Zike,Liu Zhuowei. Clinical outcome of postchemotherapy retroperitoneal lymph node dissection and predicting retroperitoneal histology in advanced nonseminomatous germ cell tumours of the testis. Chinese Journal of Surgery. 2017 Aug;55(8):603-7.

    Updated May 2020

    Yao Kai
    Title Associate Professor and Deputy Director
    Profile

    Doctor Yao is specialized in treating patients with genitourinary system cancers, including bladder, kidney, prostate, adrenal gland, ureter, urethra, testis, epididymis, spermatic cord, and penis and so on. He is good at various kinds of urological operations, especially radical inguinal lymphadenectomy. Doctor Yao perform laparscopic and open procedures to treat these cancers, often in a multi-disciplinary team approach with the integration of expertise by medical oncology and/or radiation oncology. He also pursued technical innovations which have transformed the management of these cancers including open inguinal lymphadenectomy, laparoscopic retroperitoneal lymph node dissection, open/ laparoscopic radical nephrectomy and laparoscopic radical prostatectomy. He also has unique expertise in managing rare urologic cancers and salvage procedures for recurrent cancers of the penis and kidney that have failed initial therapy with surgery or other treatments.

    Email yaokai@sysucc.org.cn
    Phone
    Research Interest(s)

     

    Education

    Doctor Yao trained in the ShangHai JiaoTong University School of Medicine. He acquired M.D in ShangHai JiaoTong University School of Medicine  and completed his Residency training in Rui Jin hospital.

    Publications

    1. Kai Yao, Hyewon Youn, Xiaoyan Gao,Bijun Huang,Fangjian Zhou, Benyi Li and Hui Han*. Casein Kinase 2 Inhibition Attenuates Androgen Receptor Function and Cell Proliferation in PC Cells. The Prostate, 72 (4):1423-1430,  2012   (IF 4.14)

    2. Kai Yao, Zai-Shang Li, Fang-Jian Zhou, Zi-Ke Qin, Zhuo-Wei Liu, Yong-Hong Li, Hui Han*. Anatomical retroperitoneoscopic retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell tumors: initial operative experience, Asian Journal of Andrology ,16 (1):136-139,  2014   (IF 2.140)

    3. Kai Yao, Peng Chen, Zi-jun Zou, Zi-Ke Qin, Zhuo-Wei Liu , Yong-Hong Li, Fang-Jian Zhou, Hui Han*. Disease specific survival after radical lymphadenectomy for penile cancer: prediction by lymph node count and density. Urologic Oncology: Seminars and Original Investigations, 2013, Dec 30. [Epub ahead of print] (IF 3.647)

    4. Kai Yao, Zi-jun Zou, Zai-shang Li, Fang-Jian Zhou, Zi-Ke Qin, Zhuo-Wei Liu, Yong-Hong Li, Hui Han*. Fascia lata preservation during inguinal lymphadenectomy for penile cancer:rationale and outcome, Urology , 82 (8):642-647,  2013   (IF 2.424)

    5. Kai Yao,  Hua Tu, Yong-Hong Li, Fang-Jian1 Zhou and Hui Han*. Modified Technique of Radical Inguinal Lymphadenectomy for Penile Carcinoma: Morbidity and Outcome, Journal of Urology, 184(8):546-552, 2011   (IF 3.696)

    6. Han H, Yao K, Zhou FJ. Modified Technique of radical inguinal lymphadenectomy to reduce the complication of skin necrosis for penile carcinoma, European Urology Supplements, 10(2): 339-340, 2011   (IF 2.162) 

    7. Han H, Youn YH, Yao K, Zhou FJ, Huang HB, Li BY. CK2-selective CK2 inhibitor: effect on AR receptor and cell cycle in castrationresistant prostate cancer cell line, European Urology Supplements, 10 (2): 292-293, 2011    (IF 2.162) 

    8. Han H, Yao K, Zhou FJ. Extroperitoneal lymph node dissection ( report of 7 cases). J of endourology .2008:22(supl 1):A286

    9.Kai Yao, Guo-Liang Hou, Yong-Hong Li,Han H and Fang-jian Zhou. Upper urinary tract dilation due to conglutination of intraluminal distal ureters after orthotopic neobladder with split-cuff nipple ureteral reimplants: Early results of 8 cases. Urologic Oncology: Seminars and Original Investigations, 27(10):611-616, 2010, (IF 3.647).


    Last Updated on: March 2015

    Li Yonghong
    Title Associate Professor and Deputy Director
    Profile

    Dr. Li specializes in diagnosis and treatment of genitourinary cancers. He focus on prostate cancer, including early diagnosis of prostate cancer with elevated PSA, open or robotic-assisted radical prostatectomy, prostate cryoablation, and comprehensive treatment of prostate cancer. He is a recognized expert in prostate cryoablation.

     
    Last Updated on: February 2016
    Email
    Phone
    Research Interest(s)


    Diagnosis of prostate cancer

    Treatment of prostate cancer with cryoablation or surgery

    Education

    2011 - Present Ph.D., Medical college, Sun Yat-sen University

    2003 - 2006  Master, Medical college, Sun Yat-sen University

    1996 – 2001 M.D., Medical college of University of South China

    Publications

    1. Li YH, Elshafei A, Agarwal G, Ruckle H, Powsang J, Jones JS. Salvage focal prostate cryoablation for locally recurrent prostate cancer after radiotherapy: initial results from the cryo on-line data registry. Prostate. 2015 Jan;75(1):1-7. (IF=3.566)

    2. Li YH, Elshafei A, Li J, Gong M, Susan L, Fareed K, Jones JS. Transrectal Saturation Technique May Improve Cancer Detection as an Initial Prostate Biopsy Strategy in Men with Prostate-specific Antigen <10 ng/ml. Eur Urol. 2014 Jun;65(6):1178-83.(IF=12.48)

    3. Li YH, Elshafei A, Li J, Hatem A, Zippe CD, Fareed K, Jones JS. Potential Benefit for Transrectal Saturation Prostate Biopsy as an Initial Biopsy Strategy: Decreased Likelihood of Finding Significant Cancer on Future Biopsy. Urology. 2014 Apr;83(4):714-8. (IF = 2.132)

    4. Elshafei A, Li YH(Co-Frist author), Hatem A, Moussa AS, Ethan V, Krishnan N, Li J, Jones JS. The utility of PSA velocity in prediction of prostate cancer and high grade cancer after an initially negative prostate biopsy. Prostate. 2013 Dec;73(16):1796-802.(IF=3.566)

    5. Liu JY, Li YH(Co-Frist author), Lin HX, Liao YJ, Mai SJ, Liu ZW, Zhang ZL, Jiang LJ, Zhang JX, Kung HF, Zeng YX, Zhou FJ, Xie D. Overexpression of YAP 1 contributes to progressive features and poor prognosis of human urothelial carcinoma of the bladder. BMC Cancer. 2013 Jul 19;13:349. doi: 10.1186/1471-2407-13-349. (IF=3.319)

    6. Liu J, Li Y(Co-Frist author), Liao Y, Mai S, Zhang Z, Liu Z, Jiang L, Zeng Y, Zhou F, Xie D. High expression of H3K27me3 is an independent predictor of worse outcome in patients with urothelial carcinoma of bladder treated with radical cystectomy. Biomed Res Int. 2013;2013: 390482. doi: 10.1155/2013/390482. (IF=2.706)

    7. Zhang ZL, Li YH(Co-Frist author), Luo JH, Liu ZW, Yao K, Dong P, Han H, Qin ZK, Chen W, Zhou FJ. Complications of radical nephrectomy for renal cell carcinoma: a retrospective study comparing transperitoneal and retroperitoneal approaches using a standardized reporting methodology in two Chinese centers. Chin J Cancer. 2013 Aug;32(8):461-8.

    8. Zhang ZL, Li YH, Xiong YH, Hou GL, Yao K, Dong P, Liu ZW, Han H, Qin ZK, Zhou FJ. Oncological outcome of surgical treatment in 336 patients with renal cell carcinoma. Chin J Cancer. 2010 Dec;29(12):995-9.

    9. Liu JY, Qian D, He LR, Li YH(Co-Frist author), Liao YJ, Mai SJ, Tian XP, Liu YH, Zhang JX, Kung HF, Zeng YX, Zhou FJ, Xie D. PinX1 suppresses bladder urothelial carcinoma cell proliferation via the inhibition of telomerase activity and p16/cyclin D1 pathway. Mol Cancer. 2013 Nov 23;12(1):148. doi: 10.1186/1476-4598-12-148.(IF=5.397)

    10. Liu JY, Li YH, Liu ZW, Zhang ZL, Ye YL, Yao K, Han H, Qin ZK, Zhou FJ. Intraarterial chemotherapy with gemcitabine and cisplatin in locally advanced or recurrent penile squamous cell carcinoma. Chin J Cancer. 2013 Nov;32(11):619-23.

    11. Hou GL, Li YH, Zhang ZL, Xiong YH, Chen XF, Yao K, Liu ZW, Han H, Qin ZK, Zhou FJ. A modified technique for neourethral anastomosis in orthotopic neobladder reconstruction. Urology. 2009 Nov;74(5):1145-9. (IF=2.132) 

    12. Elshafei A, Kartha G, Li Y, S Moussa A, Hatem A, Gao T, Jones JS. Low risk patients benefit from extreme anterior apical sampling on initial biopsy for prostate cancer diagnosis. Prostate. 2014 Sep;74(12):1183-8. (IF=3.566)

    13. Cai MY, Luo RZ, Li YH, Dong P, Zhang ZL, Zhou FJ, Chen JW, Yun JP, Zhang CZ, Cao Y. High-expression of ZBP-89 correlates with distal metastasis and poor prognosis of patients in clear cell renal cell carcinoma. Biochem Biophys Res Commun. 2012 Oct 5;426(4): 636-42. (IF=2.281)

    14. Zhang ZL, Dong P, Li YH, Liu ZW, Yao K, Han H, Qin ZK, Zhou FJ. Radical cystectomy for bladder cancer: oncologic outcome in 271 Chinese patients. Chin J Cancer. 2014 Mar 5;33(3):165-71. 

    15. Zhang ZL, Xiong YH, Li YH, Hou GL, Liu ZW, Han H, Qin ZK, Yun JP, Zhou FJ. Reassessment of the predictive role of perivesical fat invasion in invasive bladder cancer prognosis in 151 Chinese patients. Chin Med J (Engl). 2011 Sep;124(18):2915-9. (IF=1.016) 

    16. Zhang ZL, Chen W, Li YH, Liu ZW, Luo JH, Lau W, Tan MH, Zhou FJ. Stage T1N0M0 renal cell carcinoma: the prognosis in Asian patients. Chin J Cancer. 2011 Nov;30(11):772-8.

    17. Yao K, Tu H, Li YH, Qin ZK, Liu ZW, Zhou FJ, Han H. Modified technique of radical inguinal lymphadenectomy for penile carcinoma: morbidity and outcome. J Urol. 2010 Aug;184(2):546-52.(IF=3.753)

    18. Xiong YH, Zhang ZL, Li YH, Liu ZW, Hou GL, Liu Q, Yun JP, Zhang XQ, Zhou FJ. Benign pathological findings in 303 Chinese patients undergoing surgery for presumed localized renal cell carcinoma. Int J Urol. 2010 Jun;17(6):517-21. (IF=1.798)

    19. Dong P, Liu ZW, Li XD, Li YH, Yao K, Wu S, Qin ZK, Han H, Zhou FJ. Risk factors for relapse in patients with clinical stage I testicular nonseminomatous germ cell tumors. Med Oncol. 2013 Mar;30(1):494. (IF=2.058) 

    20. Zhang ZL, Liu ZW, Zhou FJ, Li YH, Xiong YH, Rao K, Hou GL, Han H, Qin ZK, Yu SL, Chen XF. Modified technique to prevent complications related to stoma and ileoureteral anastomosis in patients undergoing ileal conduit diversion. Urology. 2010 Oct;76(4):996-1000. (IF = 2.132) 

    21. Jiang L, Zhang Z, Dong P, Li Y, Yao K, Liu Z, Han H, Qin Z, Yao M, Zhou F. Efficacy of radical cystectomy plus adjuvant intraarterial chemotherapy with gemcitabine and cisplatin on locally advanced bladder cancer.  Chin Med J (Engl). 2014;127(7):1249-54. (IF=1.016)

    22. Zhang SQ, Wu S, Yao K, Dong P, Li YH, Zhang ZL, Li XX, Zhou FJ. Retroperitoneal schwannoma mimicking metastatic seminoma: case report and literature review. Chin J Cancer. 2013 Mar;32(3):149-52. 

    23. Yao K, Hou GL, Liu ZW, Yu SL, Li YH, Zhou FJ. Upper urinary tract dilation due to conglutination of intraluminal distal ureters after orthotopic neobladder with split-cuff nipple ureteral reimplants: early results of 8 cases. Urol Oncol. 2009 Nov-Dec;27(6):611-6. (IF=3.363) 


    Last Updated on: February 2016

    Zhang Zhiling
    Title Associate Professor
    Profile

    I graduated at Guangzhou Medical University as a  MD in 2006. During 2006-2012, I finished my post graduated training in Sun Yat-Sen University  Cancer Center. After that I was trained as a research fellow in one of the most famous kidney cancer center- The Cleveland Clinic. From then on I work as a full-time faculty in Sun Yat-Sen University  Cancer Center as a urologist. I am skilled in treating urological cancer, especially renal cancer, bladder cancer and prostate cancer with both minimally invasive surgery and open surgery.

    Email zhangzhl@sysucc.org.cn
    Phone 020-87343840
    Research Interest(s)

    Urological cancer, especially renal cancer, bladder cancer, minimally invasive surgery and preservation of renal function.

    Education

    Sun Yat-Sen University                                09/2009-06/2012
    Major in Oncology
    Doctor of Clinical Medicine and Doctoral Diploma issued in June 2012

    Sun Yat-Sen University                                09/2006-06/2009
    Major in Oncology
    Master of Clinical Medicine and Postgraduate Diploma issued in June 2009

    Guangzhou Medical University                     09/2001-06/2006
    Major in Clinical Medicine
    Bachelor of Medicine and Undergraduate Diploma issued in June 2006

    Publications

    1. Li Z, Liu Z, Yao K, Qin Z, Han H, Li Y, Dong P, Ye Y, Wang Y, Wu Z, Zhang Z (corresponding author), Zhou F. An improved ileal conduit surgery for bladder cancer with fewer complications. Cancer Commun (Lond). 2019 Apr 18;39(1):19

    2. Yu C, Liu Z, Chen Q, Li Y, Jiang L, Zhang Z (corresponding author), Zhou F. Nkx2.8 inhibits epithelial-mesenchymal transition in bladder urothelial carcinoma via transcriptional repression of Twist1. Cancer Res. 2018 Mar 1;78(5):1241-1252.

    3. Zhang Z, Zhao J, Dong W, Aguilar Palacios, Remer EM, Li J, Demirjian S, Zabell J, Campbell SC. Acute Ipsilateral Renal Dysfunction after Partial Nephrectomy in Patients with a Contralateral Kidney: Spectrum Score to Unmask Ischemic Injury.  Eur Urol, 2016 Oct;70(4):692-698.

    4. Zhang Z, Zhao J, Dong W, Remer EM, Li J, Demirjian S, Zabell J, Campbell SC. Acute kidney injury after partial nephrectomy: Role of parenchymal mass reduction and ischemia and impact on subsequent functional recovery. Eur Urol. 2016;69(4):745-52.

    5. Zhang Z, Zhao J, Zabell J, Remer EM, Li J, Campbell JA, Dong W, Aguilar Palacios D, Patel T, Demirjian S Campbell SC. Proteinuria in Patients Undergoing Renal Cancer Surgery: Impact on Overall Survival and Stability of Renal Function. European Urology Focus. 2016 Dec 15;2(6):616-622.

    6. Zhang Z, Zhao J, Velet L, Ercole CE, Remer EM, Mir CM, Li J, Takagi T, Demirjian S, Campbell SC. Functional Recovery from Extended Warm Ischemia Associated with Partial Nephrectomy. Urology. 2016;87:106-13.

    7. Zhao J, Zhang Z (co-first), Dong W, Remer EM, Li J, Erickson K, Patel T, Almassi N, Hinck B, Zabell J, Tourojman M, Lane BR, Campbell SC. Preoperative prediction and postoperative surgeon assessment of volume preservation with partial nephrectomy: comparison to measured volume preservation. Urology, 2016;93:124-9.

    8. Zhang ZL, Yu CP, Velet L Li YH, Jiang LJ, Zhou FJ. The difference in prognosis between renal sinus fat and perinephric fat invasion for pT3a renal cell carcinoma: a meta-analysis. PLoS One. 2016 Feb 18;11(2):e0149420.

    9. Zhang ZL, Yu CP, Li YH, Jiang LJ, Zhou FJ. Utility of SAM68 in the progression and prognosis for bladder cancer. BMC Cancer. 2015 May 6;15:364.

    10. Zhang ZL, Yu CP, Liu ZW, Velet L, Li YH, Jiang LJ, Zhou FJ. The importance of extranodal extension in penile cancer: a meta-analysis. BMC Cancer. 2015 Oct 28;15:815.

    Last updated: April 2020

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