Characterization of cancer-related genes
Xin-Yuan Guan's Laboratory

Summary
The laboratory of Xin-Yuan Guan, Ph.D. is within the State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center. The research interests of Guan Lab include the characterization of cancer-related genes, cancer stem cells and tumor microenvironment in hepatocellular carcinoma (HCC) and esophageal squamous cell carcinoma (ESCC) with multidisciplinary approaches and tools such as FISH, in vitro and in vivo functional assays, deep sequencing analysis, stemness-associated assays, and metastatic animal models. 

Current Research
1.  Identification and characterization of cancer-related genes in HCC and ESCC.

2.  Characterization of FGFR2+ cancer-associated fibroblasts(CAFs) in ESCC.

3.  Identification and characterization of cancer stem cells (CSCs) in HCC and

    ESCC.

4.  Investigation of the role of HBV X gene in HCC pathogenesis.

Contact Information
Xin-Yuan Guan, Ph.D.
Principle Investigator,
Professor
State Key Laboratory of Oncology in South China
Collaborative Innovation Center for Cancer Medicine
Sun Yat-Sen University Cancer Center

Address
Room 706, West Building,
No.651 Dongfeng Road East,
Guangzhou 510060, China.
Office: 86-20-87343166
Email: guanxy@sysucc.org.cn