Genetic mechanisms and/or prediction biomarkers of cancer metastasis
Dan Xie's Laboratory
The laboratory of Dan Xie, M.D., Ph.D. is within the Sun Yat-Sen University Cancer Center for basic and translational studies on cancer metastasis and anticancer drugs research. The Xie Lab is interested in understanding the genetic mechanisms and/or prediction biomarkers of cancer metastasis in several types of human cancers including colorectal, hepatoceullar, esophageal, lung and ovarian carcinomas.
1. The molecular carcinogenic characteristics and clinical significance of new candidate oncogene EIF5A2 in colorectal cancer metastasis.
2. The role of the Polycomb EZH2 in hepatocellular carcinoma metastasis and the screening and molecular mechanism of its silence of tumor suppressor.
3. Studies on the molecular functions and mechanism of miRNA-148 in the malignant progress of primary hepatocellular carcinoma.
Dan Xie, M.D., Ph.D.
The State Key Laboratory of Oncology in Southern China
The Department of Pathology
Sun Yat-Sen University Cancer Center
Lab729, Building 2
No. 651, Dongfeng Road East
Office: (8620) 87343193
Fax: (8620) 87343170