Our Experts

Name: Min Zheng
Title: Professor; Chief physician; Doctoral supervisor
Email: zhengmin@sysucc.org.cn

Dr Zheng is a professor of gynecological tumors at Sun Yat-sen University Cancer Center, as well as a supervisor of PhD students. Dr Zheng obtained her Bachelors in Medicine (equivalent to MD in the US) from the Medical College of Nan-Hua University, Hengyang, P. R. China in 1985 and her MD from the Medical College of Zurich University and the Medical College of Bern University, Switzerland in 2003, respectively. Her doctoral training at the University of Zurich and the University of Bern in Switzerland, and her time as a visiting scholar training at the University of Florida and the University of Puerto Rico in the USA, have provided her with great opportunities in exploring the fields of tumorigenesis, and tumor metastasis of tumor cells. 


In addition, Dr Zheng has been engaged in gynecologic oncology clinical and research work. Dr. Zheng has rich experience in the diagnosis and treatment of gynecological tumors; especially Leonardo Da Vinci robot surgeries. She is also in charge of several national, provincial and university funded grants, and has laid the groundwork for the proposed research to explore the clinical effects and mechanisms of oncogenes associated with ovarian cancer and cervical cancer. Dr Zheng has published more than 40 research papers, conducted in-depth research on the incidence of gynecological tumors and chemotherapy resistance. At the same time, she actively initiated and participated in a number of clinical trials, which are committed to the treatment of advanced and recurrent gynecological malignant tumors.



Exploring the clinical effects and mechanisms of oncogenes associated with malignant progression of ovarian cancer and cervical cancer.


04/2000-05/2003: MD degree, Medical College of Zurich University and Medical College of Bern University, Switzerland

06/1992-12/1997: Visiting scholar, Basel, Switzerland, and University of Puerto Rico, USA

09/1980-06/1985: Undergraduate, Medical College of Nan-Hua University, Hengyang, Hunan Province, P.R.China


1、 Wei Wei., Ban Xiaohua., Yang Fan., Li Jibin., Cheng Xiaqin., Zhang Rong., Huang Xin., Huang Yongwen., Li Qiaqia., Qiu Ya., Zheng Min.*, Zhu Xiaofeng., Li Jundong.(2022). Phase II trial of efficacy, safety and biomarker analysis of sintilimab plus anlotinib for patients with recurrent or advanced endometrial cancer. J Immunother Cancer, 10(5)

2、 Lan Chun-Yan., Zhao Jing., Yang Fan., Xiong Ying., Li Rong., Huang Yu., Wang Jing., Liu Chang., Bi Xue-Han., Jin Hai-Hong., Meng Jin., Zhao Wei-Hong., Zhang Li., Wang Ya-Fei., Zheng Min.*, Huang Xin.(2022). Anlotinib combined with TQB2450 in patients with platinum-resistant or -refractory ovarian cancer: A multi-center, single-arm, phase 1b trial. Cell Rep Med, 3(7), 100689. 

3、 Zhang Lan., Huang Shu-Ting., Feng Yan-Ling., Wan Ting., Gu Hai-Feng., Xu Jing., Yuan Lin-Jing., Zhou Yun., Yu Xing-Juan., Huang Long., Luo Rong-Zhen., Jia Wei-Hua., Zheng Min*.(2017). The Bidirectional Regulation between MYL5 and HIF-1α Promotes Cervical Carcinoma Metastasis. Theranostics, 7(15), 3768-3780. 

4、 Zhou Yun., Chen Chang-Long., Jiang Sen-Wei., Feng Yanling., Yuan Linjing., Chen Ping., Zhang Lan., Huang Shuting., Li Jundong., Xia Jian-Chuan., Zheng Min*.(2019). Retrospective analysis of the efficacy of adjuvant CIK cell therapy in epithelial ovarian cancer patients who received postoperative chemotherapy. Oncoimmunology, 8(2), e1528411. 

5、 Huang Shu-Ting., Chen Jing., Lian Li-Yin., Cai Hui-Hua., Zeng Hai-Shan., Zheng Min.*, Liu Mu-Biao. (2020). Intratumoral levels and prognostic significance of Fusobacterium nucleatum in cervical carcinoma. Aging (Albany NY), 12(22), 23337-23350. 

6、 Wang Jian-Hua., Huang Shu-Ting., Zhang Lan., Liu Zi-Gang., Liang Rong-Xin., Jiang Sen-Wei., Jiang Yi-Nan., Yu Xing-Juan., Jiang Yu-Chuan., Li Xi-Zhao., Zhang Pei-Fen., Wen Zhe-Sheng., Zheng Min*.(2019). Combined prognostic value of the cancer stem cell markers CD47 and CD133 in esophageal squamous cell carcinoma. Cancer Med, 8(3), 1315-1325.

7、 Yuan Lin-jing; Li Jun-dong; Zhang Lan; Wang Jian-hua; Wan Ting; Zhou Yun; Tu Hua; Yun Jing-ping; Luo Rong-zhen; Jia Wei-hua; Zheng Min*. SPAG5 upregulation predicts poor prognosis in cervical cancer patients and alters sensitivity to taxol treatment via the mTOR signaling pathway, Cell Death & Disease, 2014, 5: 0-e1247 

8、 Huang Long., Zheng Min.*, Zhou Qing-Min., Zhang Mei-Ying., Jia Wei-Hua., Yun Jing-Ping., Wang Hui-Yun.(2011). Identification of a gene-expression signature for predicting lymph node metastasis in patients with early stage cervical carcinoma. Cancer, 117(15), 3363-73.

9、 Zheng Min.*, Tang Li., Huang Long., Ding Hui., Liao Wen-Ting., Zeng Mu-Sheng., Wang Hui-Yun.(2010). Overexpression of karyopherin-2 in epithelial ovarian cancer and correlation with poor prognosis. Obstet Gynecol, 116(4), 884-891.

10Huang L, Lin J-X, Yu Y-H, Zhang M-Y, Wang H-Y, Zheng M*, Down regulation of Six MicroRNAs Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix, PLoS ONE, 7(3):e33762, 2012    IF:4.1

11、 He L, Ding H, Wang JH, Zhou Y, Li JD, Huang L, Yun JP, Luo RZ, Yu YH, Jia WH, Zeng MS and Zheng M*, Overexpression of Karyopherin 2 in Human Ovarian Malignant Germ Cell Tumor Correlates with Poor Prognosis, PLoS ONE, 7(9):e42992, 2012   IF: 4.1

12Huang L, Liao LM, Wang HY, Zheng M*, Clinicopathologic character and prognostic factors of the ovarian fibrosarcoma: results of a multi-center retrospective study, BMC cancer, 10:585, 2010    IF: 3.0

13Zheng M*, Huang L, He L, Ding H, Wang HY, and Zheng LM, Evaluation of the effects of type II radical hysterectomy in the treatment of 960 patients with stage IB-IIB cervical carcinoma: a retrospective study, J surg oncol, 103(5):435-441, 2011    IF: 2.4

14Zheng M *, Huang L, Liu JH, Xiong Y, Li JD, Huang X, He L, Ren YF and Wang HY, Type II radical hysterectomy and adjuvant therapy for pelvic lymph node metastasis with stage IB-IIB cervical carcinoma: A retrospective study of 288 patients, J surg oncol, 104(5):480-5, 2011     IF: 2.4

15Huang L, Wang HY, Zhou QM, Zhang MY, Yu YH, Jia WH, Yun JP and Zheng M*, Identification of a 7-Gene Signature that Predicts Relapse and Survival for Early Stage Cervical Carcinoma Patients, Med oncol, 29(4)2911-2918, 2012   IF: 2.2                                                    

16Liao LM, Zheng M*, Huang L, Zhang Y, Wang HY, Molecular characterization of early adenocarcinoma of the uterine cervix by oligonucleotide microarray, Arch Gynecol Obstet, 283(4):861-9, 2011     IF: 1.3

17Huang L, Zheng M*, Liu JH, Xiong Y, Ding H, Tang L,Wang HY, Risk factors and prognosis of IB-IIB cervical carcinoma with common iliac lymph node metastasis, Chin J Cancer29(4): 300-306, 2010

18Wang J-H#, Chen X-T#, Wen Z-S#, Zheng M*, Deng J-M, Wang M-Z, Lin H-X, Chen K, Li J, Yun J-P, Luo R-Z, Song L-B, High Expression of GOLPH3 in Esophageal Squamous Cell Carcinoma Correlates with Poor Prognosis, PLoS ONE,7(10): e45622, 2012   IF: 4.1

19Kocher T, Zheng M*, Bolli M, et al. Prognostic relevance of MAGE-A4 tumor antigen expression in transitional cell carcinoma of the urinary bladder: a tissue microarray study. Int J Cancer 2002,100(6):702-5.    IF: 4.7

20Zheng M*, Simon R, Mirlacher M, et al. TRIO Amplification and Abundant mRNA Expression Is Associated with Invasive Tumor Growth and Rapid Tumor Cell Proliferation in Urinary Bladder Cancer. Am J Pathol 2004, 165(1): 63-9.   IF: 6.4

21Zheng M*, Simon R, Kononen J, Sauter G, et al. Analysis of gene expression profiles among 3 epithelial ovarian tumor subtypes using cDNA and tissue microarrays. Int J Gyn Cancer 2004,14 (suppl.1):31-32.    IF: 1.9

22Zheng M*, Kuffler DP. Guidance of regenerating motor axons in vivo by gradients of diffusible peripheral nerve?derived factors. J Neurobiol 2000, 42 (2)212-19.    IF: 3.9

23郑敏*, Simon R, Kononen J, Struckmann K, Sauter G, Mihatsch MJ., Moch H。使用cDNA微阵列和组织微阵列对三种上皮性卵巢肿瘤基因表达的分析。癌症200423(7):771-776  

24郑敏*, Grogen SP, Schaffner T, Mainil-Varlet. 激光受伤的软骨诱导软骨细胞凋亡释放的凋亡因子的研究。中华医学杂志 200787(21):1496-1500   

25、唐莉、郑敏*、熊樱、丁慧、刘富元。年轻妇女卵巢上皮癌的临床特点及预后。癌症200827(9): 951-955

26Huang L, Zheng M*, Liu JH, Xiong Y, Ding H, Tang L,Wang HY. Risk factors and prognosis of IB-IIB cervical carcinoma with common iliac lymph node metastasis. Chin J Cancer 2010,29(4): 300-306

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