- Name: Qiang Liu
- Title: Professor
- Email: liuq9@mail.sysu.edu.cn
- Phone: 020-87343177
Professor Quentin Liu (Qiang Liu), is a distinguished recipient of the National Distinguished Youth Fund, awarded the title of Chang Jiang Scholar, the Leader of Creative Research Groups of the National Natural Science Foundation, and a Chief Scientist of the 973 Program. In recent years, Professor Liu has published over 200 research papers in internationally renowned academic journals such as Nature Medicine, Journal of Clinical Oncology, Cell Research, Nature Communications, Cell Metabolism, Journal of Clinical Investigation, Cancer Cell, PNAS, and Blood. He has also been granted 10 patents.
Neuroimmunotherapy for cancer stem cells;
2. Differentiation induction of cancer stem cells;
3. Biorhythmic regulation of mind-body behavior.
M.D., University of Illinois at Chicago, United States, 1994-2000
Ph.D., University of Illinois at Urabana-Champaign, United States, 1991-1997
B.S., Nanjing University, China, 1985-1989
1. Peng F, Lu J, Su K, Liu X, Luo H, He B, Wang C, Zhang X, An F, Lv D, Luo Y, Su Q, Jiang T, Deng Z, He B, Xu L, Guo T, Xiang J, Gu C, Wang L, Xu G, Xu Y, Li M, Kelley K W, Cui B and Liu Q, Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis. Cell Metab, 2024. (IF:27.7)
2. Zhang W, Zhang Z, Xiang Y, Gu D D, Chen J, Chen Y, Zhai S, Liu Y, Jiang T, Liu C, He B, Yan M, Wang Z, Xu J, Cao Y L, Deng B, Zeng D, Lei J, Zhuo J, Lei X, Long Z, Jin B, Chen T, Li D, Shen Y, Hu J, Gao S and Liu Q, Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis. Nat Struct Mol Biol, 2024. 31(2): p. 219-231. (IF:12.5)
3. He B, Gao R, Lv S, Chen A, Huang J, Wang L, Feng Y, Feng J, Liu B, Lei J, Deng B, He B, Cui B, Peng F, Yan M, Wang Z, Lam E W, Jin B, Shao Z, Li Y, Jiao J, Wang X and Liu Q, Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness. Signal Transduct Target Ther, 2023. 8(1): p. 275. (IF:40.8)
4. Liu F, Wang X, Duan J, Hou Z, Wu Z, Liu L, Lei H, Huang D, Ren Y, Wang Y, Li X, Zhuo J, Zhang Z, He B, Yan M, Yuan H, Zhang L, Yan J, Wen S, Wang Z and Liu Q, A Temporal PROTAC Cocktail-Mediated Sequential Degradation of AURKA Abrogates Acute Myeloid Leukemia Stem Cells. Adv Sci (Weinh), 2022. 9(22): p. e2104823.(IF:14.3)
5. Li S, Qi Y, Yu J, Hao Y, He B, Zhang M, Dai Z, Jiang T, Li S, Huang F, Chen N, Wang J, Yang M, Liang D, An F, Zhao J, Fan W, Pan Y, Deng Z, Luo Y, Guo T, Peng F, Hou Z, Wang C, Zheng F, Xu L, Xu J, Wen Q, Jin B, Wang Y and Liu Q, Nuclear Aurora kinase A switches m(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4. Signal Transduct Target Ther, 2022. 7(1): p. 97. (IF:40.8)
6. Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, Liu B, Lv S, Chu P, An F, Wang Z, Huang J, Zhan Y, Liao Y, Lu J, Xu L, Zhang J, Sun Z, Li Z, Wang F, Lam E W and Liu Q, Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells. Cell Res, 2021. 31(3): p. 345-361. (IF:28.1)
7. Xie J, Wang Z, Fan W, Liu Y, Liu F, Wan X, Liu M, Wang X, Zeng D, Wang Y, He B, Yan M, Zhang Z, Zhang M, Hou Z, Wang C, Kang Z, Fang W, Zhang L, Lam E W, Guo X, Yan J, Zeng Y, Chen M and Liu Q, Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma. Signal Transduct Target Ther, 2021. 6(1): p. 333. (IF:40.8)
8. Chen A, Wen S, Liu F, Zhang Z, Liu M, Wu Y, He B, Yan M, Kang T, Lam E W, Wang Z and Liu Q, CRISPR/Cas9 screening identifies a kinetochore-microtubule dependent mechanism for Aurora-A inhibitor resistance in breast cancer. Cancer Commun (Lond), 2021. 41(2): p. 121-139. (IF:20.1)
9. Cui B, Luo Y, Tian P, Peng F, Lu J, Yang Y, Su Q, Liu B, Yu J, Luo X, Yin L, Cheng W, An F, He B, Liang D, Wu S, Chu P, Song L, Liu X, Luo H, Xu J, Pan Y, Wang Y, Li D, Huang P, Yang Q, Zhang L, Zhou B P, Liu S, Xu G, Lam E W, Kelley K W and Liu Q, Stress-induced epinephrine enhances lactate dehydrogenase A and promotes breast cancer stem-like cells. J Clin Invest, 2019. 129(3): p. 1030-1046. (IF:13.3)
10. Wen H, Ma H, Cai Q, Lin S, Lei X, He B, Wu S, Wang Z, Gao Y, Liu W, Liu W, Tao Q, Long Z, Yan M, Li D, Kelley K W, Yang Y, Huang H and Liu Q, Recurrent ECSIT mutation encoding V140A triggers hyperinflammation and promotes hemophagocytic syndrome in extranodal NK/T cell lymphoma. Nat Med, 2018. 24(2): p. 154-164. (IF:58.7)

