After getting his bachelor’s degree of medicine in Zhongshan School of Medicine (equivalent to an M.D. in the USA), Dr. Yang was recommended for admission to the First Affiliated Hospital of SYSU, majoring in surgery. And then he was a joint Ph.D. student at Harvard Medical School (HMS) and Massachusetts General Hospital (MGH) for 2 years, supported by China Scholarship Council. He started his work as a surgeon at Sun Yat-sen University Cancer Center (SYSUCC) in 2018, and he was committed to the comprehensive treatment of breast cancer research. To date, He published more than 10 articles as the first author and applied for 8 patents.

1) Oncoplastic breast-conserving surgery and breast-conserving surgery.  

2) Comprehensive treatment of breast cancer and development of new treatments. 

3) Metastasis, recurrence, and drug resistance mechanism of breast cancer.

4) Prevention of complications of breast cancer treatment, such as endocrine therapy-related osteoporosis, aiming to improve the life quality of patients

Yang A*, Peng F*, Zhu L*, Li X, Ou S, Huang Z, Wu S, Peng C*, Liu P*, Kong Y*. Melatonin inhibits triple-negative breast cancer progression through the Lnc049808-FUNDC1 pathway.  Cell Death Dis. 2021 Jul 16; 12(8): 712.

Yang A*, Zhou Y*, Kong Y*, Wei X, Ye F, Zhang L, Zhong X, Li M, Lu S, An X*, Xiao W*. Identification and Validation of Immune-Related Methylation Clusters for Predicting Immune Activity and Prognosis in Breast Cancer.  Front Immunol. 2021 Jun 30; 12: 704557.

Yang A*, Wu M*, Ni M*, Zhang L, Li M, Wei P, Yang Y, Xiao W*, An X*. A risk scoring system based on tumor microenvironment cells to predict prognosis and immune activity in triple-negative breast cancer.  Breast Cancer. 2022 May; 29(3): 468-477.

Yang Z*, Yang A*, Ma W, Ma K, Lv YK, Peng P*, Zang SQ*, Li B*. Atom-precise fluorescent copper cluster for tumor microenvironment targeting and transient chemodynamic cancer therapy.  J Nanobiotechnology. 2022 Jan 6; 20(1): 20.

Bauer NC, Yang A, Wang X, Zhou Y, Klibanski A, Soberman RJ. A cross-nearest neighbor/Monte Carlo algorithm for single-molecule localization microscopy defines interactions between p53, Mdm2, and MEG3.  J Biol Chem. 2021 Jan-Jun; 296: 100540.

Liu P*, Xie X*, Yang A*, Kong Y, Allen-Gipson D, Tian Z, Zhou L, Tang H*, Xie X*. Melatonin Regulates Breast Cancer Progression by the lnc010561/miR-30/FKBP3 Axis. Mol Ther Nucleic Acids. 2020 Mar 6; 19: 765-774.

Yan R, Guo Y, Wang X, Liang G, Yang A*, Li J*. Near-Infrared Light-Controlled and Real-Time Detection of Osteogenic Differentiation in Mesenchymal Stem Cells by Upconversion Nanoparticles for Osteoporosis Therapy.  ACS Nano. 2022 May 15.

Guo Y, Yan R, Wang X, Liang G, Yang A*, Li J*. Near-Infrared Light-Controlled Activation of Adhesive Peptides Regulates Cell Adhesion and Multidifferentiation in Mesenchymal Stem Cells on an Up-Conversion Substrate. Nano Lett. 2022 Mar 23; 22(6): 2293-2302.