- Name: Wenting Liao
- Title: Professor
- Email: liaowt@sysucc.org.cn
- Phone:
Postdoctoral, Dr. DePinho Lab, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center
2008- 2010
Postdoctoral, Professor Yanqing Ding Lab, Department of Pathology, Southern Medical University, China.
2005- 2008
Sun Yat-sen University Cancer Center, China. Ph.D. in Oncology. Mentor: Prof. YiXin Zeng
2002- 2005
Sun Yat-sen University, Cancer Center, China. M.S. Oncology. Mentor: Prof. YiXin Zeng.
1997- 2002
HengYang Medical School, Hengyang, China. M.D. Clinical Medicine.
1. Zhou Y#, Zhang Y#, Li M#, Ming T#, Zhang C, Huang C, Li J, Li F, Li H, Zhao E, Shu F, Liu L, Pan X, Gao Y, Tian L, Song L*, Huang H*, Liao W*. Oncogenic KRAS drives immunosuppression of colorectal cancer by impairing DDX60-mediated dsRNA accumulation and viral mimicry. Sci Immunol. 2024 Oct 4;9(100):1.
2. Zhou Y#, Li H#, Zhang Y#, Zhao E, Huang C, Pan X, Shu F, Liu Z, Tang N*, Li F*, Liao W*. Deubiquitinase USP4 suppresses antitumor immunity by inhibiting IRF3 activation and tumor cell-intrinsic interferon response in colorectal cancer. Cancer Lett, 2024 May 1:589:216836.
3. The RNA m6A writer METTL3 in tumor microenvironment: emerging roles and therapeutic implications. Su W, Che L, Liao W*, Huang H*. Front Immunol. 2024 Jan 22;15:1335774.
4. Li J, Lan Z, Liao W, Horner JW, Xu X, Liu J, Yoshihama Y, Jiang S, Shim HS, Slotnik M, LaBella KA, Wu CJ, Dunner K, Jr., Hsu WH, Lee R, Khanduri I, Terranova C, Akdemir K, Chakravarti D, Shang X, Spring DJ, Wang YA, DePinho RA. Histone demethylase KDM5D upregulation drives sex differences in colon cancer. Nature, 2023; 619, 632-639.
5. Zhu Y#, Huang C#, Zhang C#, Zhou Y#, Zhao E, Zhang Y, Pan X, Huang H*, Liao W*, Wang X*. LncRNA MIR200CHG inhibits epithelial-mesenchymal transition in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation. Nat Commun, 2023; 14: 8141.
6. Li M#, Huang C#, Wu Y#, Zhu L, Zhang Y, Zhou Y, Li H, Liu Z, Pan X, Wang X, Qiu J*, Li F*, Liao W*. Long non-coding RNA CCL14-AS suppresses invasiveness and lymph node metastasis of colorectal cancer cells by regulating MEP1A. Cancer Cell Int, 2023 Feb 15;23(1):27-42.
7. Shi D#, Wu X#, Jian Y#, Wang J#, Huang C, Mo S, Li Y, Li F, Zhang C, Zhang D, Zhang H, Huang H, Chen X, Wang YA, Lin C, Liu G*, Song L*, Liao W*. USP14 promotes tryptophan metabolism and immune suppression by stabilizing IDO1 in colorectal cancer. Nat Commun. 2022 Sep 26;13(1):5644.; 13, 5644.
8. Huang C#, Ou R#, Chen X#, Zhang Y, Li J, Liang Y, Zhu X, Liu L, Li M, Lin D, Qiu J, Liu G, Zhang L, Wu Y, Tang H, Liu Y, Liang L, Ding Y*, Liao W*. Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC. J Exp Clin Cancer Res. 2021 Sep 28;40(1):304.
9. Wang S#, Qiu J#, Liu L#, Su C, Qi L, Huang C, Chen X, Zhang Y, Ye Y, Ding Y, Liang L*, Liao W*. CREB5 promotes invasiveness and metastasis in colorectal cancer by directly activating MET. J Exp Clin Cancer Res. 2020 Aug 25;39(1):168.
10.Zhu X#, Wang F#, Wu X, Li Z, Wang Z, Ren X, Zhou Y, Song F, Liang Y, Zeng Z, Ding Y, Liao W*, Liang L*. FBX8 promotes metastatic dormancy of colorectal cancer in liver. Cell Death Dis. 2020 Aug 14;11(8):622.
11.Liao W, Overman MJ, Boutin AT, Shang X, Zhao D, Dey P, Li J, Wang G, Lan Z, Li J, Tang M, Jiang S, Ma X, Chen P, Katkhuda R, Korphaisarn K, Chakravarti D, Chang A, Spring DJ, Chang Q, Zhang J, Maru DM, Maeda DY, Zebala JA, Kopetz S, Wang YA*, DePinho RA*. KRAS-IRF2 axis drives immune suppression and immune therapy resistance in colorectal cancer. Cancer Cell, 2019 Apr 15;35(4):559-572.
Updated November 2024 by International Office, Sun Yat-sen University Cancer Center