Our Experts

Name: Cai Xiuyu
Title: Attending Professor, Chief physician, Doctoral Advisor
Email: caixy@sysucc.org.cn
Phone:

share
Profile

Professor XiuyuCaispecializes in the immunotherapy, targeted therapy and comprehensive treatments ofmalignant tumors, including lung cancer, nasopharyngeal carcinoma, renal cancer,hepatocellular carcinoma, colorectal cancer, breast cancer,neuroendocrine tumor,etc.

Interests
The main research directions focus on precise targeted therapy and immunotherapy for malignant tumors, including susceptibility gene screening, mechanisms of tumor metastasis and drug resistance , imbalance of key signaling pathways, analysis of relevant biomarkers and clinical prognosis, and exploration of optimal clinical treatment regimens.
Education

Medical Doctor

Publications

1. Lin-Quan Tang(#), Xiao-Yun Li(#),Zhi-Ming Li(#), Zhi-Gang Liu(#), Miao-Zhen Lin(#), Huan Zhou, Qi-Wen Yu, Jian Zhou, Chong Zhao, Ze-Bin Chen, Xi-Cheng Wang, Jia-Yu Peng, Qiu-Yan Chen, Wen-Feng Fang, Yun-Peng Yang, Bei Zhang, Liang-Ping Xia, Pi-Li Hu, Wei-Han Hu, Yi-Jie Li, Hai-Qiang Mai(*), Xiu-Yu Cai(*).The efficacy and safety of apatinib plus capecitabine in platinum-refractory metastatic and/or recurrent nasopharyngeal carcinoma: a prospective, phase II trial[J].BMC Medicine.2023 Mar 16;21(1):94.

2. Pu Li(#),Tingting Chen(#),Peng Kuang(#),Fujun Liu,Zhongmin Li,Fangfang Liu,Yu Wang,Wenfeng Zhang,Xiuyu Cai(*).Aurora-AFOXO3ASKP2 axis promotes tumor progression in clear cell renal cell carcinoma and dual-targeting Aurora-ASKP2 shows synthetic lethality[J].Cell Death Dis.2022 Jul 13;13(7):606.

3. Miaozhen Lin(#), Yujuan Lu, Qiwen Yu, Zebin Chen, Jiayu Peng, Xiuyu Cai(*).Common genetic driver mutation in NSCLC and their association with thromboembolic events: A retrospective study[J].Lung Cancer. 2022 Jun 22;172:29-34.

4. Yujie Zhang(#), Yuxin Zhang, Bo Ai, Juejun Gong, Yichen Li, Shiying Yu, Xiuyu Cai(*) and Li Zhang(*).GTF2E2 is a novel biomarker for recurrence after surgery and promotes progression of esophageal squamous cell carcinoma via miR-139-5p/GTF2E2/FUS axis[J].Oncogene.2022 Feb;41(6):782-796.

5. Lei Liu(#), Tianyu Tao(#), Shihua Liu(#), Xia Yang, Xuwei Chen, Jiaer Liang, Ruohui Hong, Wenting Wang,Yi Yang, Xiaoyi Li, Youhong Zhang, Quanfeng Li, Shujun Liang, Haocheng Yu, Yun Wu, Xinyu Guo,Yan Lai, Xiaofan Ding, Hongyu Guan, Jueheng Wu, Xun Zhu, Jie Yuan, Jun Li, Shicheng Su,Mengfeng Li, Xiuyu Cai(*), Junchao Cai(*),Han Tian(*).An RFC4/Notch1 signaling feedback loop promotes NSCLC metastasis and stemness[J].Nature Communications. 2021,05,11 ;12(1) :2693.

6. Miao He(#), Qihua He(#),Xiuyu Cai(#), Jun Liu(#), Hongshen Deng, Feng Li,1Ran Zhong,Yi Lu,Haoxin Peng, Xiangrong Wu, Zisheng Chen, Shen Lao, Caichen Li, Jianfu Li, Jianxing He, Wenhua Liang(*). Intratumoral tertiary lymphoid structure (TLS) maturation is influenced by draining lymph nodes of lung cancer[J]. J Immunother Cancer. 2023 Apr;11(4):e005539.

7. Fan Ge(#), Zhenyu Huo(#), Xiuyu Cai(#), Qiyuan Hu, Wenhao Chen, Guo Lin, Ran Zhong, Zhending You, Rui Wang, Yi Lu, Runchen Wang, Qinhong Huang, Haotian Zhang, Aiqi Song, Caichen Li, Yaokai Wen, Yu Jiang, Hengrui Liang, Jianxing He, Wenhua Liang(*), Jun Liu(*). Evaluation of Clinical and Safety Outcomes of Neoadjuvant Immunotherapy Combined With Chemotherapy for Patients With Resectable Esophageal Cancer A Systematic Review and Meta-analysis[J].JAMA Netw Open. 2022 Nov 1;5(11):e2239778.

8. Hongsheng Deng(#), Jun Liu(#), Xiuyu Cai(#), Jiawei Chen,Gaetano Rocco, René Horsleben Petersen,Alex Brunelli,Calvin S.H. Ng,Thomas A. D'Amico,Wenhua Liang(*),Jianxing He(*).Radical Minimally Invasive Surgery After Immuno-chemotherapy in Initially-unresectable Stage IIIB Non-small cell Lung Cancer[J].Ann Surg. 2021 Sep 29. doi: 10.1097/SLA.0000000000005233.

Feng Li(#), Caichen Li(#), Xiuyu Cai(#), Zhanhong Xie(#), Liquan Zhou, Bo Cheng, Ran Zhong, Shan Xiong, Jianfu Li, Zhuxing Chen, Ziwen Yu, Jianxing He(*), Wenhua Liang(*).The association between CD8+ tumor-infiltrating lymphocytes and the clinical outcome of cancer immunotherapy: A systematic review and meta-analysis [J]. EClinicalMedicine. 2021 Sep 16;41:101134.

Where are we | Contact us|

Copyright:Sun Yat-sen University Cancer Center Designed by Wanhu.