As an oncological urologist, Dr. Liu specializes in the surgical treatment of urinary tumors, especially in robotic and minimally invasive laparoscopic surgeries, as well as the comprehensive treatment of bladder cancer and testicular cancer, and the surgical treatment of children's tumors. He is one of the first surgeons in China to carry out robot-assisted/laparoscopic retroperitoneal lymph node dissection for testicular cancer and ultra-expanded lymph node dissection for bladder cancer. He has been awarded the Outstanding Contribution Award for the Highest Volume of 3-4 level difficulty Surgeries as the chief professor of Sun Yat-sen University Cancer Center. He has undertaken more than 10 research projects with funding from the National Natural Science Foundation of China and the Guangdong Natural Science Foundation, and published more than 40 articles as the first author (corresponding author), participated in editing six academic works, and served as the deputy chief editor of Bladder Cancer.

Minimally invasive surgery for Urological oncology.

Multidisciplinary management for bladder cancer and testicular cancer

1998-2000  Bachelor and Master Degree of Medicine, Medical School of Sun Yat-sen University, Guangzhou, China

2003-2006  Doctoral Degree in Oncology, Sun Yat-sen University, Guangzhou, China

Visiting scholar
2004-2005  Department of Urology, Hokkaido University, Sapporo, Japan (Training for laparoscopic surgery)

2011-2012  Department of Urology, UT Southwestern Medical Center, Dallas, United States, visiting assistant professor

1. Zhou Zhaohui, Gan Wenyi, Li Zhiyong, Li Zhen, Zhou Fangjian, Li Hua, Liu Zhuowei, Can prophylactic tamsulosin reduce the risk of urinary retention after surgery? A systematic review and meta-analysis of randomized control trials, International Journal of Surgery. (2023)

2. Zhou Zhaohui, Li Zhiyong, Zhang Zhiling, Yao Kai, Ma Huali, Guo Shengjie, Dong Pei, Ye Yunlin, Zhou Fangjian, Liu Zhuowei, Surgical Technique of Extraperitonealizing Ileal Conduit Decrease Parastomal Hernia Complication: A Single-Center, Prospective, Randomized, Controlled Clinical Trial, Journal of Urology. (2023)

3. Ma Zikun, Li Xiangdong, Mao Yize, Wei Chen, Huang Zhuoli, Li Guibo, Yin Jianhua, Liang Xiaoyu, Liu Zhuowei, Interferon-dependent SLC14A1(+) cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer, Cancer Cell. (2022)

4. Chen Lei, Liu Zefu, Tang Huancheng, Zhou Zhaohui, Chen Jiawei, Ma Zikun, Deng Minhua, Li  Xiangdong, Wu Yuanzhong, Zheng Lisi, Zhou Liwen, Zheng Xianchong, Liu Zhuowei, Knockdown of ZBTB11 impedes R-loop elimination and increases the sensitivity to cisplatin by inhibiting DDX1 transcription in bladder cancer, Cell Proliferation. (2022)

5. Ma Zikun, Mao Yize, Wang Yuanyuan, Duan Zhizhou, Qu Diyang, Li Chaofeng, Chen Runsen, Liu Zhuowei, Suicidal ideation and attempted suicide among cancer patients during the COVID-19 pandemic, Journal of Medical Virology. (2022)

6. Xiaofei Sun, Zijun Zhen, Ying Guo, Yuanhong Gao, Juan Wang, Yu Zhang, Jia Zhu, Suying Lu, Feifei Sun, Junting Huang, Ruiqing Cai, Yizhuo Zhang, Juncheng Liu, Zizheng Xiao, Sihui Zeng and Zhuowei Liu, Oral Metronomic Maintenance Therapy Can Improve Survival in High-RiskNeuroblastoma Patients Not Treated with ASCT or Anti-GD2 Antibodies, Cancers.(2021)

 

7. Wen-Su Wei, Ning Wang, Minhua Deng, Pei Dong, Jian-ye Liu, Zhen Xiang, Xiang-Dong Li, Zhi-yong Li, Zhen-hua Liu, Yu-lu Peng, Zhen Li, Li-Juan Jiang, Kai Yao, Yun-lin Ye, Wen-hua Lu , ZhiLing Zhang, Fang-Jian Zhou, Zhuo-Wei Liu, Dan Xie, Chun-ping Yu, LRPPRC regulates redoxhomeostasis via the circANKHD1/FOXM1 axis to enhance bladder urothelialcarcinoma tumorigenesis, Redox Biology.(2021)

 

8. Zhiyong Li, Lijuan Jiang, Zhiling Zhang, MinhuaDeng,Wensu Wei, Huancheng Tang, Shengjie Guo,Yunlin Ye, Kai Yao, ZhuoweiLiu, Fangjian Zhou,Long noncoding RNAs to predict postoperative recurrence in bladder cancer and to develop a new molecular classificationsystem, cancer medicine.(2021)

 

9. Zhiyong Li , Zhiling Zhang, Huali Ma , Kai Yao, Zike Qin，Hui Han , Yunlin Ye, Yonghong Li , Pei Dong, Lijuan Jiang, Li Tian, Zhuowei Liu, Fangjian Zhou, Extraperitonealization of ileal conduit reduces parastomal hernia after cystectomy and ileal conduit diversion, UrologicOncology: Seminars and Original Investigations.(2021)

 

10. Jiangli Lu, Yijun Zhang, Chenyan Wu, Chengbiao Chu, Zhuowei Liu and Yun Cao, Impact of immunohistochemistry-base molecular subtype on predicting chemotherapy response and survival in patients with T1 stage bladder cancer after bladder-preserving treatment, Japanese Journal of Clinical Oncology.(2020)

 

11. Yuanyuan Wang, Zhizhou Duan, Zikun Ma, YizeMao, Xiyuan Li, Amanda Wilson, Huiying Qin, Jianjun Ou, Ke Peng, Fangjian Zhou, Chaofeng Li, Zhuowei Liu and Runsen Chen, Epidemiology of mental health problems among patients with cancer during COVID-19 pandemic, TranslationalPsychiatry.(2020)

 

12. Liu, ZF (Liu, Zefu); Zhang, T (Zhang, Tong);Ma, ZK (Ma, Zikun); Zheng, SY (Zheng, Shiyang); Chen, JY (Chen, Junying); Wu, ZM (Wu, Zhiming); Zheng, X(Zheng, Xia); Li, XD (Li, Xiangdong); Liu, ZW (Liu,Zhuowei), Systemic Management for Nonmetastatic Castration-resistant Prostate Cancer A Systematic Review and Network Meta-Analysis, AMERICAN JOURNAL OFCLINICAL ONCOLOGY-CANCER CLINICAL TRIALS.(2020)

 

13. Shengjie Guo, Zefu Liu, Xiangdong Li, Kai Yao, Pei Dong, Dong Chen, Chunxian Liao, Zhaolin Long, Yongqiang Wang, Fangjian Zhou, Xiaobo He, Zhuowei Liu, The prognostic value of the site of invasion inT3aN0M0 clear cell renal cell carcinoma, Urologic Oncology: Seminars and Original Investigations, Volume 37, Issue 5, 2019, Pages301.e11-301.e17

 

14. Li X, Dong P, Wei W, Jiang L, Guo S, Huang C,Liu Z, Chen J, Zhou F, Xie D, Liu Z. Overexpression of CEP72Promotes Bladder Urothelial Carcinoma Cell Aggressiveness via Epigenetic CREB-Mediated Induction of SERPINE1. Am J Pathol. 2019Jun;189(6):1284-1297.

 

15. Li XD, Huang CW, Liu ZF, Jiang LJ, Chen JW, XieD, Zhou FJ, Lu HM, Liu ZW. Prognostic Role of the Immunoscore for Patients with Urothelial Carcinoma of the Bladder Who Underwent Radical Cystectomy. Ann Surg Oncol 26, 4148–4156 (2019).

 

16. Shao-Xu Wu, Jian Huang, Zhuowei Liu,Hai-Ge Chen, Pi Guo, Qing-Qing Cai, Jun-Jiong Zheng, Hai-De Qin, Zao-Song Zheng, Xin Chen, Rui-Yun Zhang, Si-Liang Chen, Tian-Xin Lin. A Genomic-clinicopathologic Nomogram for the Preoperative Prediction of Lymph Node Metastasis in Bladder Cancer. EBioMedicine, 2018, 54-65

 

17. Yu C, Liu Z, Chen Q, Li Y, Jiang L,Zhang Z, Zhou F. Nkx2.8 Inhibits Epithelial-Mesenchymal Transition in Bladder Urothelial Carcinoma via Transcriptional Repression of Twist1. CancerRes. 2018 Mar 1;78(5):1241-1252

 

18. Zefu Liu, Shiyang Zheng, Xiangdong Li, Shengjie Guo, Yanjun Wang, Fangjian Zhou, Zhuo Wei Liu. Oncologic Outcomes of Patients Undergoing Diagnostic Ureteroscopy Before Radical Nephroureterectomy for Upper Urinary Tract Urothelial Carcinomas: A Systematic Review and Meta-Analysis. J Laparoendosc Adv Surg Tech A. 2018Nov;28(11):1316-1325

 

19. Liu Z, Ye Y, Li X, Guo S, Jiang L, Dong P, Li Y, Shi Y, Fan W, Cao Y, Yao K, Qin Z, Han H, Zhou F, Liu Z. The effects of intra-arterial chemotherapy on bladder preservation in patients with T1stage bladder cancer. World J Urol. 2018 Aug;36(8):1191-1200.

 

20. Li Z, Liu Z, Yao K, Qin Z, Han H, Li Y, Dong P, Ye Y, Wang Y, Wu Z, Zhang Z, Zhou F. Modified Ileal Conduit Has Fewer Complications Related to Stoma and Ureteroileal Anastomosis as Compared with Conventional Bricker. Cancer Commun (Lond). 2019 Apr18;39(1):19.

Updated July 2023 by International Office, Sun Yat-sen University Cancer Center