Dr. Hao-Xian Yang is currently an attending surgeon in the Department of Thoracic Surgery at Sun Yat-sen University Cancer Center. He specialized in surgical treatment of lung cancer, esophageal cancer and mediastinal tumors. Dr. Yang had been a research fellow at Memorial Sloan-Kettering Cancer Center between 2014-2015. His primary research interest is minimally invasive surgery of thoracic tumors, including robotic and VATS lobectomy, segmentectomy, MIE, and robotic thymectomy. As one of the pioneered thoracic surgeon in China, Dr. Yang serves as the Director of Robotic and Minimally Invasive Surgery Branch of Guangdong Association of Thoracic Oncology, Secretary-General of Thoracic Medical Doctor Branch of Guangdong Medical Doctor Association, Deputy Director of Oncology Branch Youth Committee of Guangdong Medical Association, and Committee Member of Medical Robot Doctor Branch of Chinese Medical Doctor Association.

Minimally invasive surgery of thoracic tumors, including robotic and VATS lobectomies, segmentectomies, minimally invasive esophagectomies, and robotic thymectomies.

1999.9—2004.6 Doctoral candidate at the Thoracic Surgery Department, Sun Yat-sen University Cancer Center.

1994.9—1999.6 Sun Yat-sen University of Medical Sciences (Now Known as Medical College of Sun Yat-Sen University), Bachelor of clinical medicine.

Honors
1. 2018 ESTS-AATS GRAHAM FOUNDATION AWARD

2. Champion of 2017 Chinese Youth Thoracic Surgeon VATS Competition (Lung Cancer Group).

1. Yang MZ, Hou X, Li JB, Cai JS, Yang J, Li S, Long H, Fu JH, Zhang LJ, Lin P, Rong TH, Yang HX *. Impact of L4 lymph node dissection on long-term survival in left-side operable non-small-cell lung cancer: a propensity score matching study. Eur J Cardiothorac Surg. 2020 Feb 4. pii: ezaa008. doi: 10.1093/ejcts/ezaa008. [Epub ahead of print] PMID: 32016340

2. Yang MZ, Hou X, Liang RB, Lai RC, Yang J, Li S, Long H, Fu JH, Lin P, Wang X, Rong TH, Yang HX*. The incidence and distribution of mediastinal lymph node metastasis and its impact on survival in patients with non-small-cell lung cancers 3 cm or less: data from 2292 cases. Eur J Cardiothorac Surg. 2019 Jan 18. doi: 10.1093/ejcts/ezy479. [Epub ahead of print] PMID: 30668665

3. Liang RB, Yang J, Zeng TS, Long H, Fu JH, Zhang LJ, Lin P, Wang X, Rong TH, Hou X, Yang HX*. Incidence and Distribution of Lobe-Specific Mediastinal Lymph Node Metastasis in Non-small Cell Lung Cancer: Data from 4511 Resected Cases. Ann Surg Oncol. 2018 Oct;25(11):3300-3307. PMID:30083835

4. Hou X, Gong R, Zhan J, Zhou T, Ma Y, Zhao Y, Zhang Y, Chen G, Zhang Z, Ma S, Chen X, Gao F, Hong S, Luo F, Fang W, Yang Y, Huang Y, Chen L, Yang H*, Zhang L*. p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells. BMC Cancer. 2018 Jun 7;18(1):641. doi: 10.1186/s12885-018-4559-3.PMID: 29879950

5. Yang J, Luo GY, Liang RB, Zeng TS, Long H, Fu JH, Xu GL, Yang MZ, Li S1, Zhang LJ, Lin P, Wang X, Hou X, Yang HX*. Efficacy of Endoscopic Ultrasonography for Determining Clinical T Category for Esophageal Squamous Cell Carcinoma: Data From 1434 Surgical Cases. Ann Surg Oncol. 2018 Jul;25(7):2075-2082. doi: 10.1245/s10434-018-6406-9.

6. Yang HX, Woo KM, Sima CS, Bains MS, Adusumilli PS, Huang J, Finley DJ, Rizk NP, Rusch VW, Jones DR, Park BJ. Long-term Survival Based on the Surgical Approach to Lobectomy For Clinical Stage I Nonsmall Cell Lung Cancer: Comparison of Robotic, Video-assisted Thoracic Surgery, and Thoracotomy Lobectomy. Ann Surg. 2017 Feb;265(2):431-437.

7. Yang HX. Long-term survival of early-stage non-small cell lung cancer patients who underwent robotic procedure: a propensity score-matched study. Chin J Cancer. 2016 Jul 7;35(1):66.

8. Hou X, Liang RB, Wei JC, Xu Y, Fu JH, Luo RZ, He JH, Zhang LJ, Lin P, Yang HX*. Cyclin D1 expression predicts postoperative distant metastasis and survival in resectable esophageal squamous cell carcinoma. Oncotarget. 2016 May 24;7(21):31088-96. doi: 10.18632/oncotarget.9078. PMID: 27145270; IF: 6.359 

9. Hou X, Wei JC, Fu JH, Wang X, Luo RZ, He JH, Zhang LJ, Lin P, Yang HX*. Vascular Endothelial Growth Factor is a Useful Predictor of Postoperative Distant Metastasis and Survival Prognosis in Esophageal Squamous Cell Carcinoma. Ann Surg Oncol. 2015 Oct;22(11):3666-73

10. Hou X, Gu YK, Liu XW, Fu JH, Wang X, Zhang LJ, Luo RZ, Lin P, Yang HX*. The Impact of Tumor Cell Differentiation on Survival of Patients with Resectable Esophageal Squamous Cell Carcinomas. Ann Surg Oncol. 2015 Mar;22(3):1008-14.

11. Hou X, Fu JH, Wang X, Zhang LJ, Liu QW, Luo KJ, Lin P, Yang HX*. Prophylactic thoracic duct ligation has unfavorable impact on overall survival in patients with resectable oesophageal cancer. Eur J Surg Oncol. 2014 May；22; 40(12): 1756-1762. PMID: 24913091. IF:3.01

12. Hou X, Wei JC, Fu JH, Wang X, Zhang LJ, Lin P, Yang HX*. Proposed Modification of the Seventh American Joint Committee on Cancer Staging System for Esophageal Squamous Cell Carcinoma in Chinese Patients. Ann Surg Oncol. 2014 Jan;21(1):337-42.

13. Yang HX, Feng W, Wei JC, Zeng TS, Li ZD, Zhang LJ, Lin P, Luo RZ, He JH, Fu JH. Support Vector Machine-Based Nomogram Predicts Postoperative Distant Metastasis for Patients with Oesophageal Squamous Cell Carcinoma. Br J Cancer. 2013 Sep 3;109(5):1109-16.

14. Hou X, Wei JC, Wu JX, Wang X, Fu JH, Lin P, Yang HX*. Multidisciplinary modalities achieve encouraging long-term survival in resectable limited-disease esophageal small cell carcinoma. PLoS One. 2013 Jul 9;8(7):e69259.

15. Yang HX*, Fu JH. Reply：Should we omit tumor location as a variable when staging esophageal squamous cell carcinoma in the Chinese population? Ann Thorac Surg. 2013 Jun;95(6):2210.

16. Hou X, Wei JC, Xu Y, Luo RZ, Fu JH, Zhang LJ, Lin P, Yang HX*. The Positive Lymph Node Ratio Predicts Long-term Survival in Patients with Operable Thoracic Esophageal Squamous Cell Carcinoma in China. Ann Surg Oncol. 2013 May;20(5):1653–1659.

17. Yang HX, Hou X, Liu QW, Zhang LJ, Liu JG, Lin P, Fu JH. Tumor Location Does Not Impact Long-term Survival in Patients with Operable Thoracic Esophageal Squamous Cell Carcinoma in China. Ann Thorac Surg. 2012 Jun; 93(6):1861-6.

18. Liang Y, Hou X, Cui Q, Kang TB, Fu JH, Zhang LJ, Luo RZ, He JH, Zeng YX, Yang HX*. Skp2 expression unfavorably impacts survival in resectable esophageal squamous cell carcinoma. J Transl Med. 2012 Apr 25;10(1):73.

19. Hou X, Li Y, Luo RZ, Fu JH, He JH, Zhang LJ, Yang HX*. High expression of the transcriptional co-activator p300 predicts poor survival in resectable non-small cell lung cancers. Eur J Surg Oncol. 2012 Jun;38(6):523-30.

20. Yang HX, Wei JC, Xu Y, Liu JG, Lin P, Rong TH, Fu JH. Modification of nodal categories in the seventh American Joint Committee on Cancer staging system for esophageal squamous cell carcinoma in chinese patients. Ann Thorac Surg. 2011 Jul;92(1):216-24.

21. Li Y#, Yang HX#, Luo RZ, Zhang Y, Li M, Wang X, Jia WH. High expression of p300 has an unfavorable impact on survival in resectable esophageal squamous cell carcinoma. Ann Thorac Surg. 2011 May;91(5):1531-8. PMID: 21524463 (IF: 3.85)

22. Yang HX, Ling L, Zhang X, Lin P, Rong TH, Fu JH. Outcome of elderly patients with oesophageal squamous cell carcinoma after surgery. Br J Surg. 2010 Jun;97(6):862-7.

23. Yang HX, Xu Y, Fu JH, Wang JY, Lin P, Rong TH. An Evaluation of the Number of Lymph Nodes Examined and Survival for Node-Negative Esophageal Carcinoma: Data from China. Ann Surg Oncol. 2010 Jul;17(7):1901-11.)

24. Yang HX, Hou X, Lin P, Yang H, Zeng CG, Rong TH, Fu JH. Peripheral direct adjacent lobe invasion non-small cell lung cancer has a similar survival to that of parietal pleural invasion T3 disease. J Thorac Oncol. 2009 Nov;4(11):1342-6.

25. Yang HX, Hou X, Lin P, Rong TH, Yang H, Fu JH. Survival and risk factors of surgically treated mediastinal invasion T4 non-small cell lung cancer. Ann Thorac Surg. 2009 Aug;88(2):372-8.

Updated May 2020 by International Office, Sun Yat-sen University Cancer Center