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Name: Yun Cao
Title: Associate Professor
Email: caoyun@sysucc.org.cn
Phone:
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Dr. Cao is an associate professor from the Department of Pathology of Sun Yat-sen University Cancer Center. Dr. Cao obtained his Bachelor in Medicine (equivalent to MD in the US) and PhD at Gannan Medical College and Sun Yat-sen University, P. R. China in 1998 and 2012, respectively. After working as a general pathologist for 10 years, Dr. Cao now is focus in the field of genitourinary pathology. Besides the pathological diagnosis, Dr. Cao is also interested in the research of genitourinary tumors, especially the tumor associated fiibroblasts and tumor related Inflammatory cells. 

Between 2009 and 2011, Dr. Cao was trained in the Laboratory of Cancer Genetics, Van Andel Research Institute, Grand Rapids, MI for 6 months and in the National Cancer Centre Singapore for 11 months as an exchange scholar. Dr. Cao has published 17 research papers.

Interests
Genitourinary tumors, especially the tumor associated firbroblasts and tumor related Inflammatory cells.
Education

2008.09-2012.12 Ph.D., Sun Yat-sen University, Guangzhou, P.R. China

2001.09-2004.06 Master in Oncology, Sun Yat-sen University, Guangzhou, P.R. China

1993.09-1998.06 M.D., Gannan Medical College, Ganzhou, P.R. China

Publications

1) Li XH, He F, Yan SM, Li Y, Cao Y, Huang CY, Zhou ZW. Increased expression of stomatin-like protein 2 (STOML2) predicts decreased survival in gastric adenocarcinoma: a retrospective study. Med Oncol. 2014 Jan;31(1):763. 

2) Tang LQ, Chen QY, Fan W, Liu H, Zhang L, Guo L, Luo DH, Huang PY, Zhang X, Lin XP, Mo YX, Liu LZ, Mo HY, Li J, Zou RH, Cao Y, Xiang YQ, Qiu F, Sun R, Chen MY, Hua YJ, Lv X, Wang L, Zhao C, Guo X, Cao KJ, Qian CN, Zeng MS, Mai HQ. Prospective study of tailoring whole-body dual-modality [18F]fluorodeoxyglucose positron emission tomography/computed tomography with plasma Epstein-Barr virus DNA for detecting distant metastasis in endemic nasopharyngeal carcinoma at initial staging. J Clin Oncol. 2013 Aug 10;31(23):2861-9. 

3) Fu J, Qiu H, Cai M, Pan Y, Cao Y, Liu L, Yun J, Zhang CZ. Low cyclin F expression in hepatocellular carcinoma associates with poor differentiation and unfavorable prognosis. Cancer Sci. 2013 Apr;104(4):508-15.

4) Cao Y, Zhang ZL, Zhou M, Elson P, Rini B, Aydin H, Feenstra K, Tan MH, Berghuis B, Tabbey R, Resau JH, Zhou FJ, Teh BT, Qian CN. Pericyte coverage of differentiated vessels inside tumor vasculature is an independent unfavorable prognostic factor for patients with clear cell renal cell carcinoma. Cancer. 2013 Jan 15;119(2):313-24. 

5) Zhang CZ, Pan Y, Cao Y, Lai PB, Liu L, Chen GG, Yun J. Histone deacetylase inhibitors facilitate dihydroartemisinin-induced apoptosis in liver cancer in vitro and in vivo. PLoS One. 2012;7(6):e39870.

6) Cai MY, Luo RZ, Li YH, Dong P, Zhang ZL, Zhou FJ, Chen JW, Yun JP, Zhang CZ*, Cao Y*. High-expression of ZBP-89 correlates with distal metastasis and poor prognosis of patients in clear cell renal cell carcinoma: ZBP-89 expression in CCRCC. Biochem Biophys Res Commun. 2012 Oct 5;426(4):636-42. 

7) Zhang CZ, Cao Y, Yun JP, Chen GG, Lai PB. Increased expression of ZBP-89 and its prognostic significance in hepatocellular carcinoma. Histopathology. 2012 Jun;60(7):1114-24.

8) Ong CK, Subimerb C, Pairojkul C, Wongkham S, Cutcutache I, Yu W, McPherson JR, Allen GE, Ng CC, Wong BH, Myint SS, Rajasegaran V, Heng HL, Gan A, Zang ZJ, Wu Y, Wu J, Lee MH, Huang D, Ong P, Chan-on W, Cao Y, Qian CN, Lim KH, Ooi A, Dykema K, Furge K, Kukongviriyapan V, Sripa B, Wongkham C, Yongvanit P, Futreal PA, Bhudhisawasdi V, Rozen S, Tan P, Teh BT. Exome sequencing of liver fluke-associated cholangiocarcinoma. Nat Genet. 2012 May 6;44(6):690-3.

9) Cao Y, Xiao-Ping Miao, Yi-Xin Zeng, Dong-Xin Lin, and Jian-Yong Shao. Association between genetic polymorphisms of CYP2A13, CYP2A6 and risk of nasopharyngeal carcinoma in southern Chinese population. Cancer Biology 2011; 1(1): 1-7

10) Shao JY, Cao Y, Miao XP, Huang MY, Deng L, Hao JJ, Liang XM, Hu LF, Ernberg I, Lin DX, Zeng YX. A single nucleotide polymorphism in the matrix metalloproteinase 2 promoter is closely associated with high risk of nasopharyngeal carcinoma in Cantonese from southern China. Chin J Cancer. 2011 Sep;30(9):620-6.

11) Li XJ, Ong CK, Cao Y, Xiang YQ, Shao JY, Ooi A, Peng LX, Lu WH, Zhang Z, Petillo D, Qin L, Bao YN, Zheng FJ, Chia CS, Iyer NG, Kang TB, Zeng YX, Soo KC, Trent JM, Teh BT, Qian CN. Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis. Cancer Res. 2011 Apr 15;71(8):3162-72.

12) Zhang WD, Chen JY, Cao Y, Liu QY, Luo RG. Computed tomography and magnetic resonance imaging findings of slitary fibrous tumors in the pelvis: Correlation with histopathological findings. Eur J Radiol. 2011 Apr;78(1):65-70.

13) Zhang WD, Li CX, Liu QY, Hu YY, Cao Y, Huang JH. CT, MRI, and FDG-PET/CT imaging findings of abdominopelvic desmoplastic small round cell tumors: Correlation with histopathologic findings. Eu J Radiol. 2011 Nov; 80(2):269-73.

14) Li M, Luo RZ, Chen JW, Cao Y, Lu JB, He JH, Wu QL, Cai MY. High expression of transcriptional coactivator p300 correlates with aggressive features and poor prognosis of hepatocellular carcinoma. J Transl Med. 2011 Jan 5;9:5.

15) Ding PR, An X, Cao Y, Wu XJ, Li LR, Chen G, Lu ZH, Fang YJ, Wan DS, Pan ZZ. Depth of Tumor Invasion Independently Predicts Lymph Node Metastasis in T2 Rectal Cancer. J Gastrointest Surg. 2011 Jan;15(1):130-6.

16) Cao Y, Miao XP, Huang MY, Deng L, Liang XM, Lin DX, Zeng YX, Shao JY. Polymorphisms of methylenetetrahydrofolate reductase are associated with a high risk of nasopharyngeal carcinoma in a smoking population from southern China. Mol Carcinog. 2010 Nov;49(11):928-34.

17) Cao Y, Miao XP, Huang MY, Deng L, Lin DX, Zeng YX, Shao JY. Polymorphisms of death pathway genes FAS and FASL and risk of nasopharyngeal carcinoma. Mol Carcinog. 2010 Nov;49(11):944-50.





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