With over 30 years of clinical experience, he has trained more than 30 master’s and doctoral students. He has led over 10 scientific research projects, including the National Natural Science Foundation of China and major scientific and technological plans of Guangdong Province. He has published more than 100 academic papers in journals such as JNS and Neuro-oncology, and has authored two books published by the People’s Medical Publishing House. He holds 16 utility model patents, 5 invention patents, and has 2 translational patents. He has received the First Prize of Guangdong Provincial Medical Science and Technology Award and the 6th “National Famous Doctor - Outstanding Contribution” Award from People’s Daily. He is a Senior Expert in Health Care in Guangdong Province and a Clinical Medical Scientist at Sun Yat-sen University Cancer Center, specializing as the Chief Expert in Glioma.

Chairman of the Neuro-Oncology Expert Committee of the Chinese Society of Clinical Oncology (CSCO)
Chairman of the Brain Glioma Professional Committee of the Chinese Anti-Cancer Association
Incoming Chairman of the Neurosurgery Branch of the Guangdong Medical Association
Member of the Neurosurgery Branch of the Chinese Medical Doctors Association
Deputy Leader of the Chinese Brain Metastasis Tumor Collaborative Group
Vice Chairman of the Neuro-Oncology Branch of the Chinese Society for Neuroscience
Vice Chairman of the Neuro-Oncology Subcommittee of the Chinese Anti-Cancer Association

The diagnosis and microsurgery of central nervous system tumors; comprehensive treatment of gliomas (surgery, chemotherapy, targeted therapy, and immunotherapy); translational research and clinical treatment of brain metastases.

1985.9-1990.6 Binzhou Medical College, Bachelor of Clinical medicine ;

1997.9-2000.6  Sun Yat-sen University, Master of Neurosurgery

2002.9-2005.6   Sun Yat-sen University, Doctor of Neurosurgery

2007.11-12  Kaohsiung Medical University, Post Doctor Fellowship

2009.6.-12  M.D. Anderson Cancer Center, Visiting Scholar

1. Duan H, Ren J, Wei S, Yang Z, Li C, Wang Z, Li M, Wei Z, Liu Y, Wang X et al: Integrated analyses of multi-omic data derived from paired primary lung cancer and brain metastasis reveal the metabolic vulnerability as a novel therapeutic target. Genome Med 2024, 16(1):138. PMID: 39593114

2.Duan H, Xie Y, Wu S, Zhao G, Zeng Z, Hu H, Yu Y, Hu W, Yang Y, Chen Y et al: Effect of the mRNA decapping enzyme scavenger (DCPS) inhibitor RG3039 on glioblastoma. J Transl Med 2024, 22(1):880. PMID: 39350123; PMCID: PMC11443721.

3.Yang W, Han Y, He C, Zhong S, Ren F, Chen Z, Mou Y, Sai K. Association between psychiatric disorders and glioma risk: evidence from Mendelian randomization analysis. BMC Cancer. 2024 Jan 23;24(1):118. doi: 10.1186/s12885-024-11865-y. PMID: 38262954; PMCID: PMC10807081.

4. Sheng Zhong, Wenzhuo Yang, Zhiyun Zhang, Yangyiran Xie, Lin Pan, Jiaxin Ren, Fei Ren, Yifan Li, Haoqun Xie, Hongyu Chen, Davy Deng, Jie Lu, Hui Li, Bo Wu, Youqi Chen, Fei Peng, Vinay K. Puduvalli, Ke Sai, Yunqian Li, Ye Cheng & Yonggao Mou .Association between viral infections and glioma risk: a two-sample bidirectional Mendelian randomization analysis.BMC Medicine.2023 Dec 5;21(1):487.

5. Wang T, Zhou Y, Fan Y, Duan H, Guo X, Chang J, Jiang Y, Li C, Fu Z, Gao Y, Guo X, Sidlauskas K, He Z, Da Costa C, Sheng X, Wu D, Yuan J, Li H, He Y, Mou Y, Li N. PERK-Mediated Cholesterol Excretion from IDH Mutant Glioma Determines Anti-Tumoral Polarization of Microglia. Adv Sci (Weinh). 2023 Jul;10(20):e2205949.

6. Guo C, Yang Q, Xu P,Deng M,Jiang T, Cai L et al. Adjuvant Temozolomide Chemotherapy With or Without Interferon Alfa Among Patients With Newly Diagnosed High-grade Gliomas: A Randomized Clinical Trial. JAMA Netw Open. 2023;6(1):e2253285.

7. Lun Liang, Zhenning Wang, Hao Duan, Zhenqiang He, Jie Lu, Xiaobing Jiang, Hongrong Hu,Chang Li, Chengwei Yu, Sheng Zhong, Run Cui, Xiaoyu Guo, Meiling Deng, Yuanyuan Chen, Xiaojing Du, Shaoxiong Wu, Likun Chen, Yonggao Mou.Survival Benefits of Radiotherapy and Surgery in Lung Cancer Brain Metastases with Poor Prognosis Factors.Current Oncology. 2023 Feb 13;30(2):2227-2236

8. Lun Liang, Liangbao Wen,Shixing Qin, Zhenqiang He, Jie Lu, Run Cui, Xiaobing Jiang, Hongrong Hu, Sheng Zhong, Chang Li, Chengwei Yu, Yuang Xie, Zhenning Wang,  Hao Duan, Yonggao Mou.Poor Karnofsky performance status is not a contraindication for neurosurgical resection in patients with lung cancer brain metastases: a multicenter, retrospective PSM-IPTW cohort study.Journal of neuro-oncology.Journal of neuro-oncology. 2023;162(2):327-335

9. Lu J, Wang Z, He Z, Hu Y, Duan H, Liu Z, Li D, Zhong S, Ren J, Zhao G, Mou Y, Yao M. Oligomer-Aβ42 suppress glioma progression via potentiating phagocytosis of microglia. CNS Neurosci Ther. 2024 Jan;30(1):e14495. doi: 10.1111/cns.14495. Epub 2023 Oct 17. PMID: 37849438; PMCID: PMC10805446.

10. Zhong S, Ren JX, Yu ZP, Peng YD, Yu CW, Deng D, Xie Y, He ZQ, Duan H, Wu B, Li H, Yang WZ, Bai Y, Sai K, Chen YS, Guo CC, Li DP, Cheng Y, Zhang XH, Mou YG. Predicting glioblastoma molecular subtypes and prognosis with a multimodal model integrating convolutional neural network, radiomics, and semantics. J Neurosurg. 2022 Dec 2;139(2):305-314. doi: 10.3171/2022.10.JNS22801. PMID: 36461822.