Dr. Luo Donghua is an attending physician. She graduated with the doctoral degree in Clinical Oncology from Sun Yat-sen University in 2010. At present, she serves as the attending physician in Sun Yat-sen University Cancer Center. Her research interests are in chemotherapy, radiation therapy, combination therapy for nasopharyngeal carcinoma; prevention and treatment of  radiotherapy side reaction; the mechanism of nasopharyngeal carcinoma distant metastasis and its prevention & treatment.

Chemotherapy, radiation therapy, combination therapy for nasopharyngeal carcinoma; prevention and treatment of  radiotherapy side reaction; the mechanism of nasopharyngeal carcinoma distant metastasis and its prevention & treatment.

09/1996-07/2001 Undergraduate studies under the Seven-year Program of Clinical Medicine, Zhongshan School of Medicine, SYSU

09/2001-07/2003 Postgraduate studies (master’s degree) under the Seven-year Program of Clinical Medicine, Zhongshan School of Medicine, SYSU

09/2007-07/2010 On-job doctoral degree’s program of Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center

 

1. Bao YN, Cao X, Luo DH (Co-first author), Sun R, Peng LX, Wang L, Yan YP, Zheng LS, Xie P, Cao Y, Liang YY, Zheng FJ, Huang BJ, Xiang YQ, Lv X, Chen QY, Chen MY, Huang PY, Guo L, Mai HQ, Guo X, Zeng YX, Qian CN. Urokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis. Cell Cycle. 2014;13(12):1958-69. (IF 5.25)

2. Luo DH, Chen QY, Liu H, Xu LH, Zhang HZ, Zhang L, Tang LQ, Mo HY, Huang PY, Guo X, Mai HQ. The independent, unfavorable prognostic factors endothelin A receptor and chemokine receptor 4 have a close relationship in promoting the motility of nasopharyngeal carcinoma cells via the activation of AKT and MAPK pathways. J Transl Med. 2013; 11(1):203. (IF 3.5)

3. Mo HY, Luo DH（Co-first author）, Qiu HZ, Liu H, Chen QY, Tang LQ, Zhong ZL, Huang PY, Zhao ZJ, Zhang CQ, Zhang Y, Mai HQ. Elevated serum endostatin levels are associated with poor survival in patients with advanced-stage nasopharyngeal carcinoma. Clin Oncol (R Coll Radiol). 2013;25(5):308-17. doi: 10.1016/j.clon.2012.11.009. (IF 2.1)

4. Liu H, Huang PY, Tang LQ, Chen QY, Zhang Y, Zhang L, Guo L, Luo DH, Mo HY, Xiang YQ, Qiu F, Sun R, Chen MY, Hua YJ, Lv X, Wang L, Zhao C, Guo X, Cao KJ, Qian CN, Hong MH, Mai HQ. Functional polymorphisms of matrix metalloproteinase-9 and survival in patients with locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy. Med Oncol. 2013;30(4):685. doi: 0.1007/s12032-013-0685-6. Epub 2013 Aug 18.

5. Tang LQ, Chen QY, Fan W, Liu H, Zhang L, Guo L, Luo DH, Huang PY, Zhang X, Lin XP, Mo YX, Liu LZ, Mo HY, Li J, Zou RH, Cao Y, Xiang YQ, Qiu F, Sun R, Chen MY, Hua YJ, Lv X, Wang L, Zhao C, Guo X, Cao KJ, Qian CN, Zeng MS, Mai HQ. Prospective study of tailoring whole-body dual-modality [18F]fluorodeoxyglucose positron emission tomography/computed tomography with plasma epstein-barr virus DNA for detecting distant metastasis in endemic nasopharyngeal carcinoma at initial staging. J Clin Oncol. 2013;31(23):2861-9. doi: 10.1200/JCO.2012.46.0816. Epub 2013 Jul 15.

6. Lin HX, Hua YJ, Chen QY, Luo DH, Sun R, Qiu F, Mo HY, Mai HQ, Guo X, Xian LJ, Hong MH, Guo L. Randomized study of sinusoidal chronomodulated versus flat intermittent induction chemotherapy with cisplatin and 5-fluorouracil followed by traditional radiotherapy for locoregionally advanced nasopharyngeal carcinoma. Chin J Cancer. 2013; 32(9):502-11. doi: 10.5732/cjc.013.10004. Epub 2013 Jul 2.

7. Tang Y, Luo DH, Rong X, Shi X, Peng Y. Psychological disorders, cognitive dysfunction and quality of life in nasopharyngeal carcinoma patients with radiation-induced brain injury. PLoS ONE. 2012;7(6):e36529. (IF 4.1)

8. Chen MY, Wang SL, Zhu YL, Shen GP, Qiu F, Luo DH, Chen QY, Jiang R, Cao KJ, Qian CN, Hong MH. Use of a posterior pedicle nasal septum and floor mucoperiosteum flap to resurface the nasopharynx after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma. Head & Neck. 2012; 34(10):1383-8. (IF 2.4)

9. Chen QY, Wen YF, Guo L, Liu H, Huang PY, Mo HY, Li NW, Xiang YQ, Luo DH, Qiu F, Sun R, Deng MQ, Chen MY, Hua YJ, Guo X, Cao KJ, Hong MH, Qian CN, Mai HQ. Concurrent chemoradiotherapy vs. radiotherapy alone in stage II nasopharyngeal carcinoma: phase III randomized trial. J Natl Cancer Inst. 2011 Nov 4. (IF 14.69)

10. Tang Y, Li Y, Luo DH, Rong X, Ye J, Peng Y. Epilepsy related to radiotherapy in patients with nasopharyngeal carcinoma. Epilepsy Res. 2011;96(1-2):24-8. (IF 2.3)

11. Tang Y, Luo DH, Peng W, Huang F, Peng Y. Ocular ischemic syndrome secondary to carotid artery occlusion as a late complication of radiotherapy of nasopharyngeal carcinoma. J Neuroophthalmol. 2010;30(4):315-20.(IF 1.08)

12. Huang PY, Mai HQ, Luo DH, Qiu F, Li NW, Xiang YQ, Chen QY, Zhang L, Sun R, Cao KJ, Guo L, Deng MQ, Mo HY, Guo X, Zhang F, Cao SM, Chen MY, Guo Y, Fan YY, Hu W, Hua YJ, Xie GF, Hong MH. Controlled study on induction-concurrent chemoradiotherapy and induction chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma. Chinese Journal of Cancer. 2009;28(10):1033-1042.

13. Huang PY, Cao KJ, Guo X, Mo HY, Guo L, Xiang YQ, Deng MQ, Qiu F, Cao SM, Guo Y, Zhang L, Li NW, Sun R, Chen QY, Luo DH, Hua YJ, Mai HQ, Hong MH. A randomized trial of induction chemotherapy plus concurrent chemoradiotherapy versus induction chemotherapy plus radiotherapy for locoregionally advanced nasopharyngeal carcinoma. Oral Oncol. 2012; 48(10):1038-44. (IF 2.857)

14. Luo DH, Cao JY, Ji H, Zhang H, Zeng MS, Hong MH. Preliminary analysis of the whole-genome-microarray-based results of peripheral blood in nasopharyngeal carcinoma patients. Chinese Journal of Cancer Prevention and Treatment. 2011;18(9):641-646.

15. Luo DH, Hong MH, Xiao XB. Analysis of the correlation between the saliva epidemal growth factor concentration and oral mucositis during nasopharyngeal carcinoma radiotherapy. Chinese Journal of Radiation Oncology. 2008;17(6):478-479.

16. Luo DH, Hong MH, Guo L, et al. Multivariable analysis of the oral mucositis during nasopharyngeal carcinoma radiotherapy and the clinical value of constructing the discriminative model. Chinese Journal of Cancer. 2005;24(7):850-854.

17. Luo DH, Guo L, Hong MH, Zhang F. Nasopharyngeal carcinoma with meningeal intracranial metastases: a case report. Chinese Journal of Oncology. 2005;27(1):62.

18. Luo DH, Hong MH. The mechanism, prevention and treatment of radioactive oral mucosal injuries. The Journal of Practical Medicine. 2003;19(2)205-207.

19. Cao KJ, Zhang AL, Ma WJ, Huang PY, Luo DH, Xia WX. Nedaplatin or cisplatin combined with 5-fluorouracil for treatment of stage III-IVa nasopharyngeal carcinoma: a randomized controlled study. Chinese Journal of Oncology. 2011;33(1)50-2

20. Ma WJ, Cao KJ, Xia WX, Luo DH. The relationship between re-staging and prognosis of recurrent nasopharyngeal carcinoma on the primary focus. China Cancer. 2010;Issue 11.

21. Huang PY, Hong MH, Zhang X, Mai HQ, Luo DH. The C-KIT expression and mutation in nasopharyngeal carcinoma cell lines and their reaction to Imatinib. Chinese Journal of Cancer. 2010;Issue 2.

22. Huang PY, Zhang L, Zhang X, Hong MH, Mai HQ, Luo DH. The mutation of C-KIT gene in patients with nasopharyngeal carcinoma. China Oncology. 2009;Issue 4.

23. Guo L, Lin HX, Qiu F, Luo DH, et al. Clinical experience in treating elderly patients with advanced nasopharyngeal carcinoma by using Capecitabine Tablets plus Paraplatin combined with concurrent chemoradiotherapy. Cancer Research on Prevention and Treatment. 2006;Issue 5.

24. Hua YJ, Hong MH, Luo DH, et al. Multivariable analysis of prognostic predictors for 406 patients with nasopharyngeal carcinoma. Chinese Journal of Clinical Oncology. 2005;32(8):435-438.

25. Hong MH, Mai HQ, Luo DH. Cost-effectiveness analysis of the adjuvant chemotherapy for N2-3 patients with nasopharyngeal carcinoma. China Cancer. 2000;9(12):548.

26. Shi XL, Ma SS, Luo DH, Rong XM, Li ZC, Fu RY, Shen QY, Tang YM. Clinical research on radiation-induced optic neuropathy in patients with nasopharyngeal carcinoma. Chinese Journal of Neuromedicine. 2013;12(1):76-79.

27. Li Y, Tang YM, Luo DH, Rong XM, Ye JH, Peng Y. Epilepsy related to radiotherapy in patients with nasopharyngeal carcinoma. Chinese Journal of Neuromedicine. 2012;11(10):986-988.

Updated by International Office, Sun Yat-sen University Cancer Center