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Name: Wanli Liu
Title: Chief Technician,Chief of Department of Laboratory Medicine
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1987-1998, Senior technician, The department of Clinical Laboratory, Shaanxi Provincial People's Hospital.

2003-2014, Chief technician, Department of Laboratory Medicine, Sun Yet-sen University Cancer Center.

Interests

Implementation of new tumor marker tests which will improve programs for the early detection of nasopharyngeal carcinoma.

Development of a panel of tumor tests that may aid in the early detection of lung cancer.

Education
1998-2003, Chongqing Medical University , Doctor, Clinical laboratory diagnostics.
Publications

1. Liu WL, Lin YH, Xiao H, Xing S, Chen H, Chi PD, Zhang G.Epstein-Barr Virus Infection Induces Indoleamine 2,3-Dioxygenase Expression in Human Monocyte-Derived Macrophages through p38/Mitogen-Activated Protein Kinase and NF-κB Pathways: Impairment in T Cell Functions.J Virol. 2014 ;88(12):6660-71. 

2. Zheng X, Xing S, Liu XM, Liu W, Liu D, Chi PD, Chen H, Dai SQ, Zhong Q, Zeng MS, Liu WL.Establishment of using serum YKL-40 and SCCA in combination for the diagnosis of patients with esophageal squamous cell carcinoma.BMC Cancer. 2014 Jul 7;14(1):490. 

3. Chen H, Chi P, Wang W, Li L, Luo Y, Fu J, Zhang L, Liu W. Evaluation of a semi-quantitative ELISA for IgA antibody against Epstein-Barr virus capsid antigen in the serological diagnosis of nasopharyngeal carcinoma. Int J Infect Dis. 2014:110-5. 

4. Wang JY, Zheng YZ, Yang J, Lin YH, Dai SQ, Zhang G, Liu WL(). Elevated levels of serum amyloid A indicate poor prognosis in patients with esophageal squamous cell carcinoma. BMC Cancer. 2012 ;12:365. (IF=3.0)

5、Dong J, Zeng BH, Xu LH, Wang JY, Li MZ, Zeng MS, Liu WL(). Anti-CDC25B autoantibody predicts poor prognosis in patients with advanced esophageal squamous cell carcinoma. J Transl Med. 2010 ;8:81.(IF=3.5)

6、 Liu WL, Guo XZ, Zhang LJ, Wang JY, Zhang G, Guan S, Chen YM, Kong QL, Xu LH, Li MZ, Song LB, Zeng MS.Prognostic relevance of Bmi-1 expression and autoantibodies in esophageal squamous cell carcinoma. BMC Cancer. 2010 ;10:467.

7、 Liu WL, Zhang G, Wang JY, Cao JY, Guo XZ, Xu LH, Li MZ, Song LB, Huang WL, Zeng MS. Proteomics-based identification of autoantibody against CDC25B as a novel serum marker in esophageal squamous cell carcinoma. Biochem Biophys Res Commun. 2008 ;375(3):440-5.

8. Zhang G, Liu WL, Zhang L, Wang JY, Kuang MH, Liu P, Lin YH, Dai SQ, Du J.Involvement of indoleamine 2,3-dioxygenase in impairing tumor-infiltrating CD8 T-cell functions in esophageal squamous cell carcinoma. Clin Dev Immunol. 2011;2011:384726. 

9. Liu Y, Huang Q, Liu W(共同第一), Liu Q, Jia W, Chang E, Chen F, Liu Z, Guo X, Mo H, Chen J, Rao D, Ye W, Cao S, Hong M. Establishment of VCA and EBNA1 IgA-based combination by enzyme-linked immunosorbent assay as preferred screening method for nasopharyngeal carcinoma: a two-stage design with a preliminary performance study and a mass screening in southern China. Int J Cancer. 2011 Aug 22. doi: 10.1002/ijc.26380. 

10. Xu YF, Liu WL, Dong JQ, Liu WS, Feng QS, Chen LZ, Zeng YX, Zeng MS, Jia WH. Sequencing of DC-SIGN promoter indicates an association between promoter variation and risk of nasopharyngeal carcinoma in cantonese. BMC Med Genet. 2010 ;11:161. 

11. Tang L, Yang J, Liu W, Tang X, Chen J, Zhao D, Wang M, Xu F, Lu Y, Liu B, Sun Q, Zhang L, He F Liver sinusoidal endothelial cell lectin, LSECtin, negatively regulates hepatic T-cell immune response. Gastroenterology. 2009 ;137(4):1498-508.

12. Pan K, Wang H, Liu WL, Zhang HK, Zhou J, Li JJ, Weng DS, Huang W, Sun JC, Liang XT, Xia JC. The pivotal role of p38 and NF-kappaB signal pathways in the maturation of human monocyte-derived dendritic cells stimulated by streptococcal agent OK-432. Immunobiology. 2009;214(5):350-8. 

13. Guo XZ, Zhang G, Wang JY, Liu WL, Wang F, Dong JQ, Xu LH, Cao JY, Song LB, Zeng MS. Prognostic relevance of Centromere protein H expression in esophageal carcinoma. BMC Cancer. 2008 ;8:233.

14. Sun JC, Pan K, Chen MS, Wang QJ, Wang H, Ma HQ, Li YQ, Liang XT, Li JJ, Zhao JJ, Chen YB, Pang XH, Liu WL, Cao Y, Guan XY, Lian QZ, Xia JC. Dendritic cells-mediated CTLs targeting hepatocellular carcinoma stem cells. Cancer Biol Ther. 2010 ;10(4):368-75. 

15. Song LB, Li J, Liao WT, Feng Y, Yu CP, Hu LJ, Kong QL, Xu LH, Zhang X, Liu WL, Li MZ, Zhang L, Kang TB, Fu LW, Huang WL, Xia YF, Tsao SW, Li M, Band V, Band H, Shi QH, Zeng YX, Zeng MS. The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells. J Clin Invest. 2009 ;119(12):3626-36.

 

Last updated on: February, 2015  by International Office, Sun Yat-sen University Cancer Center

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