Li Li-ren | Colorectal Surgery | Sun Yat-sen University Cancer Center-Sun Yat-sen University Cancer Center

Name: Li Li-ren

Title: Associate Professor and Deputy Director of Colorectal Department

Email: patient_home@163.com

Phone:

Profile

Dr. Li-ren Li is associate professor and deputy director of colorectal department of Sun Yat-sen University Cancer Center. Dr. Li obtained his Bachelor in Medicine (equivalent to MD in the US) and PhD at Sun Yat-sen University of Medical Sciences, P. R. China in 1998 and 2005, respectively. He received surgical training at Queen Elizabeth Hospital of University of Adelaide, Australia from 2003 to 2004, learning laparoscopic colorectal resection. He was appointed as associate professor in 2007 and deputy director of colorectal department in 2009. He worked as a visiting scientist at Harvard medical school Dana-Farber cancer institute and University of Texas MD Anderson Cancer Center under the supervision of Prof. Ronald Depinho and Prof. Lynda Chin from 2010 to 2013, offering him with great opportunities to explore the fields of tumorigenesis, tumor metabolism, tumor metastasis, and drug resistance of tumor cells. He rejoined Sun Yat-sen University Cancer Center at the end of 2013, and focuses on multiple disciplinary therapy model of colorectal cancer and molecular mechanism of tumor metastasis. Dr. Li has published more than 20 research papers.

Interests

Multiple disciplinary therapy model of colorectal cancer and molecular mechanism of tumor metastasis.

Education

Tertiary
Sun Yat-Sen University of Medical Science (SYSU)
Clinical Medicine Department
MBBS obtained in1998

Internship
1997 First Affiliated Hospital of SYSU
Medical Science Medicine

M.S. in Surgery
1998-2000
Thesis: “Comparison of MeshPlug Hernia Repair and Bassini Repair”
Supervisor: Prof Yihua Huang

M.D., Ph.D. in Oncology
2002-2005 SYSUC
Thesis: “Relationship between Lymphangiogenesis and Local Invasion, Lymphatic Metastasis in ColorectalCarcinoma”
Supervisor: Prof Desen Wan Sun Yat-Sen University of Medical ScienceSun Yat-Sen University of Medical ScienceSun Yat-Sen University of Medical Science

Publications

1. Ian R. Watson, Liren Li, Peter K. Cabeceiras, et al. The RAC1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of RAF. Cancer Research, 2014 (accepted).

2. Wang G, Gao Y, Li L, Jin G, Cai Z, Chao JI, Lin HK. K63-linked ubiquitination in kinase activation and cancer. Front Oncol. 31, 2(5): 1-13, 2012.

3. Ding Z, Wu CJ, Jaskelioff M, Ivanova E, Kost-Alimova M, Protopopov A,Chu GC, Wang G, Lu X, Labrot ES, Hu J, Wang W, Xiao Y, Zhang H, Zhang J, Zhang J, Gan B, Perry SR, Jiang S, Li L, Horner JW, Wang YA, Chin L, DePinho RA. Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases. Cell. 148(5): 896-907, 2012.

4. Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, Voet D, Saksena G, Stransky N, Onofrio RC, Winckler W, Ardlie K,Wagle N, Wargo J, Chong K, Morton DL, Stemke-Hale K, Chen G, Noble M, Meyerson M,Ladbury JE, Davies MA, Gershenwald JE, Wagner SN, Hoon DS, Schadendorf D, Lander ES, Gabriel SB, Getz G, Garraway LA, Chin L. A landscape of driver mutations in melanoma. Cell. 150(2):251-63, 2012.

5. Comprehensive molecular characterization of human colon and rectal cancer. Nature. 487(7407):330-7, 2012.

6. Li LR;Fang YJ;Pan ZZ;Wu XJ;Wan DS;Hardingham JE;Rieger N. Length of lymphangiogenesis in the rectal tissues distal to rectal cancer. Tumour Biol. 31(6): 667-71, 2010.

7. Fang YJ;Pan ZZ;Li LR;Lu ZH;Zhang LY;Wan DS. MMP7 expression regulated by endocrine therapy in ERbeta-positive colon cancer cells. Journal of experimental & clinical cancer research, 2009, 28: 132.

8. Li LR, Wan DS, Pan ZZ, et al. Expression of hTERT in activated lymphocytes using real-time RT-PCR. Journal of Colorectal & Anal Surgery, 2007: 7-10.

9. Li LR, Wan DS, Pan ZZ, et al. Prognostic effect of lymphatic spreading of colorectal cancer.GuangdongProvinceJournal of Medicine, 2006: 1819-1821.

10. Li LR, Wan DS, Pan ZZ, et al. Predictive mathematical model for lymphatic metastasis of colorectal cancer. Bulletin of Chinese Cancer, 2006: 876-878.

11. Li LR, Wan DS, Pan ZZ, et al. Effect of clinicopathologic parameters on lymphatic metastasis of colorectal cancer.ChinaTropical Medicine, 2006:1160-1163.

12. Li LR, Wan DS, Pan ZZ, et al. Clinical feature and treatment strategy of anal canal adenocarcinoma. Chinese Journal of Gastrointestinal Surgery, 2006: 402-404.

13. Li LR, Wan DS. Advance in lymphangiogenesis of colorectal cancer, 2006: 382-384.

14. Li LR, Wan DS, Pan ZZ, et al. Relationship between VEGFR-3 and Prox1 incolorecal cancer.GuangdongProvinceJournal of Medicine, 2005: 1488-1490.

15. Li LR, Pan ZZ, Nick Rieger, et al. Clinical significance of expression of hTERT in colorectal cancer. Aizheng, 2004: 1502-1507.

16. Li LR, Huang YH. Comparison between tension-free inguinal hernia repair and Bassini repair. Chinese Journal of General Surgery, 2001: 47-49.

Book chapters

1. Li LR, Wan DS. Appendix adenoma and carcinoid. Colorectal Cancer, Peking: Chinese Medical Science Publishing House, 2004.

2. Li LR, Wan DS. Large bowel perforation. Stoma rehabilitation and treatment: theory and practice, Peking: Chinese Medical Science Publishing House, 2006.

3. Li LR, Wan DS.Melanoma in anorectum. Colorectal cancer, Peking: Peking University MedicalPress, 2008.

Last updated on: July, 2014

Our Experts