Sun Yat-sen University Cancer Center

Name: Man Nie

Title: Associate Chief Physician, Master’s supervisor

Email: nieman@sysucc.org.cn

Phone:

share

Profile

She has published 18 papers in academic journals, including Nat Cancer,Cell Mol Immunol,JCI,Clin Cancer Res, Cell Rep, Adv Sci,Clin Transl Med,and Cell Death Dis, serving as the (co)-first, (co-)corresponding author. Additionally, she has received funding from multiple competitive grants, including the National Natural Science Foundation of China (Young Scientist programme), the Natural Science Foundation of Guangdong Province (General program), the Guangzhou Basic and Applied Basic Research Scheme, and the China Postdoctoral Science Foundation.

Interests

Clinical and Translational Studies in Lymphoma.

Education

2017-2019: Exchange PhD student supported by China Scholarship Council. Department of Bioscience and Nutrition, Karolinska Institutet, Stockholm, Sweden.

2014-2019: PhD in Medical Oncology.

Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guang Zhou, China.

2009-2014: Bachelor in Clinical Medicine. Sun Yat-sen University, Guang Zhou, China.

Publications

1. Nie M#,*, Lei D#, Liu Z#, Zeng K#, Liang X#, Huang P, Wang Y, Sun P, Yang H, Liu P, Nie R, Huang S, Song E, Jiang W, Li Z, Yang Y*, Xia Y*, Yang L*. Cardiomyocyte-localized CCDC25 senses extracellular NET-DNA to promote doxorubicin cardiotoxicity by activating autophagic flux.Nature Cancer.2025 Aug;6(8):1400-1418. (First author and Co-corresponding author).

2. Wang S#, Liang X#, Li H#, Zou J#, Xu L#, Zhang Y, Lin J, Zeng J, Zhong X, Liu X, Liu Z, Zheng Y*,Nie M*, Yang L*. The NET-DNA-CCDC25 inhibitor di-Pal-MTO suppresses tumor progression and promotes the innate immune response.Cell Mol Immunol. 2025 Jun;22(6):628-644. (Co-corresponding author).

3. Huang S#, Lei D#, Yang L#, Bi A#, Wang Y, Zhang P, Zhuang D, Liu H, Cai Q*,Nie M*, Xia Y*, Tumor-associated sympathetic nerves promote the progression of Epstein-Barr virus-positive diffuse large B-cell lymphoma.Adv. Sci. 2025, e13580. (Co-corresponding author).

4. Ye X#, Wang L#,Nie M#, Wang Y, Dong S, Ren W, Li G, Li Z*, Wu K*, Pan-Hammarstrom Q*. A single-cell atlas of diffuse large B cell lymphoma. Cell Reports. 2022; 39(3):110713.(Co-first author).

Nie M#, Ren W#, Ye X#, Berglund M#, Wang X#, Fjordén K, Du L, Giannoula Y, Lei D, Su W, Li W, Liu D, Linderoth J, Jiang C, Bao H, Jiang W, Huang H, Hou Y, Zhu S, Enblad G, Jerkeman M, Wu K*, Zhang H*, Amini RM*, Li ZM*, Pan-Hammarström Q*. The dual role of CD70 in B-cell lymphomagenesis. Clin Transl Med. 2022 Dec;12(12):e1118.(First author).

Our Experts