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Name: Xiangdong Li
Title: Chief Physician
Email: lixiangd@sysucc.org.cn
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Dr. Li graduated from Sun Yat-sen University and serves in the Department of Urology at Sun Yat-sen University Cancer Center. He specializes in the surgical treatment of bladder cancer, testicular cancer, renal pelvic and ureteral cancer, and pediatric tumors. His research focuses on health services and outcomes research in testicular and bladder cancers. 
Interests
Bladder cancer, Testicular cancer
Education
Publications

1. Xiangdong Li , Renjie Ding , Zhenhua Liu , Wilhem M S Teixeira , Jingwei Ye , Li Tian , Haojiang Li , Shengjie Guo , Kai Yao , Zikun Ma , Zhuowei Liu. A predictive system comprising serum microRNAs and radiomics for residual retroperitoneal masses in metastatic nonseminomatous germ cell tumors. Cell Reports Medicine.2024 Dec 17;5(12):101843.  

 

2. Zikun Ma, Yuzhao Wang , Weikai Wang , Chen Wei , Zhenhua Liu , Zhiyong Li , Yunlin Ye , Yize Mao , Yunfei Yuan , Zhenkun Huang , Ji Zhang , Yun Cao , Xiaopeng Mao , Yan Zhang , Xin Jin , Jianhua Yin , Guibo Li , Limin Zheng , Zhaoyuan Liu , Xiangdong LiCorrespondence author, Xiaoyu Liang, Zhuowei Liu. Targeting VSIG4+ tissue-resident macrophages enhances T cell cytotoxicity and immunotherapy efficacy in cancer. Development Cell. 2025 Apr 29:S1534-5807(25)00249-7. 


3. Zikun Ma , Xiangdong Lico-first author, Yize Mao , Chen Wei , Zhuoli Huang , Guibo Li  Jianhua Yin , Xiaoyu Liang , Zhuowei Liu. Interferon-dependent SLC14A1+ cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer. Cancer Cell. 2022 Dec 12;40(12):1550-1565.e7. 

 

4. Li Xiangdong , Zhang J X, Jiang L J, Wang F W, Liu L L, Liao Y J, Jin X H, Chen W H, Chen X, Guo S J, Zhou F J, Zeng Y X, Guan X Y, Liu Zhuo-Wei, Xie D. Overexpression of maelstrom promotes bladder urothelial carcinoma cell aggressiveness by epigenetically downregulating MTSS1 through DNMT3B. Oncogene. 2016 Dec 8;35(49):6281-6292. 

 

5. Li Xiangdong, Dong P, Wei W, Jiang L, Guo S, Huang C, Liu Z, Chen J, Zhou F, Xie D, Liu Z. Overexpression of CEP72 Promotes Bladder Urothelial Carcinoma Cell Aggressiveness via Epigenetic CREB-Mediated Induction of SERPINE1. Am J Pathol. 2019 Jun;189(6):1284-1297.  

 

6. Li Xiangdong,, Huang CW, Liu ZF, Jiang LJ, Chen JW, Xie D, Zhou FJ, Lu HM, Liu ZW. Prognostic Role of the Immunoscore for Patients with Urothelial Carcinoma of the Bladder Who Underwent Radical Cystectomy. Ann Surg Oncol. 2019 Nov;26(12):4148-4156. doi: 10.1245/s10434-019-07529-y.

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