Our Experts

Name: Zhang Quan
Title: Professor, Doctoral advisor and Deputy Director of the Department of Head and Neck Surgery
Email: zhangquan@sysucc.org.cn
Dr. Zhang Quan is a professor of Head and Neck Surgery Department of Sun Yat-sen University Cancer Center. Dr. Zhang obtained his Bachelor in Medicine (equivalent to MD in the US) and PhD at Sun Yat-sen University of Medical Sciences, P. R. China in 1987 and 1997, respectively. He joined the Department of Head and Neck Surgery at Sun Yat-sen University Cancer Center (SYSUCC) as a resident doctor in 1987 and promoted to attending doctor in 1994. In late 2001, Dr. Zhang promoted to vice-Professor and the deputy director of the Department of Head and Neck Surgery. Since Dec. 2010, he was appointed as chief physician. Professor Zhang has been working at the diagnosis and therapy of head and neck tumors since 1987. He is especially sophisticated in treatment of laryngeal cancer with function preservation, thyroid carcinoma, tissue coagulation with microwave for oral cancer and neck dissection. Dr. Zhan has published 27 research papers since 2004 and 8 academic monographs as associate editor or a member of the editorial board.

The diagnosis and therapy of head and neck tumors, and especially the treatment of laryngeal cancer with function preservation, thyroid carcinoma, tissue coagulation with microwave for early laryngeal cancer and neck dissection.


MD, Sun Yat-sen University of Medical Sciences, P. R. China, 1981-1987.

Master in Surgical Oncology, Sun Yat-sen University of Medical Sciences, P. R. China, 1992-1994.

PhD in Surgical Oncology, Sun Yat-sen University of Medical Sciences, P. R. China, 1994-1997.


1. Li R, Chen S, Zhan J, Li X, Liu W, Sheng X, Lu Z, Zhong R, Chen L, Luo X, Hu Y, Ouyang Y, Liu T, Zhang Q*, Zhang S. Long noncoding RNA FOXD2-AS1 enhances chemotherapeutic resistance of laryngeal squamous cell carcinoma via STAT3 activation. Cell Death Dis. 2020 Jan 20;11(1):41. doi: 10.1038/s41419-020-2232-7. PubMed PMID: 31959918; PubMed Central PMCID: PMC6971019.

2. Chen SW, Li SH, Shi DB, Jiang WM, Song M, Yang AK, Li YD, Bei JX, Chen WK, Zhang Q. Expression of PD-1/PD-L1 in head and neck squamous cell carcinoma and its clinical significance. Int J Biol Markers. 2019 Dec;34(4):398-405. doi: 10.1177/1724600819884722. Epub 2019 Nov 1. PubMed PMID: 31674884.

3. Chen SW, Zhang Q#, Guo ZM, Chen WK, Liu WW, Chen YF, Li QL, Liu XK, Li H, Ou-Yang D, Chen WC, Fu XY, Wang XD, Yang AK, Bei JX, Song M. Trends in clinical features and survival of oral cavity cancer: fifty years of experience with 3,362 consecutive cases from a single institution. Cancer Manag Res. 2018 Oct 12;10:4523-4535. doi: 10.2147/CMAR.S171251. eCollection 2018. PubMed PMID: 30349385; PubMed Central PMCID: PMC6190823.

4. Mao Y, Fu Y, Gao Y, Yang A, Zhang Q. Platelet-to-lymphocyte ratio predicts long-term survival in laryngeal cancer. Eur Arch Otorhinolaryngol. 2018 Feb;275(2):553-559. doi: 10.1007/s00405-017-4849-4. Epub 2017 Dec 23. PubMed PMID: 29275426.

5. Fu Y, Mao Y, Chen S, Yang A, Zhang Q. A Novel Inflammation- and Nutrition-Based Prognostic System for Patients with Laryngeal Squamous Cell Carcinoma: Combination of Red Blood Cell Distribution Width and Body Mass Index (COR-BMI). PLoS One. 2016 Sep 22;11(9):e0163282. doi: 10.1371/journal.pone.0163282. PubMed PMID: 27658208; PubMed Central PMCID: PMC5033418.

6. Fu Y, Chen SW, Chen SQ, Ou-Yang D, Liu WW, Song M, Yang AK, Zhang Q. A Preoperative Nutritional Index for Predicting Cancer-Specific and Overall Survival in Chinese Patients with Laryngeal Cancer: A Retrospective Study. Medicine (Baltimore). 2016 Mar;95(11):e2962. doi: 10.1097/MD.0000000000002962. PubMed PMID: 26986105; PubMed Central PMCID: PMC4839886.

7. Fu Y, Liu W, OuYang D, Yang A, Zhang Q. Preoperative Neutrophil-to-lymphocyte Ratio Predicts Long-term Survival in Patients Undergoing Total Laryngectomy with Advanced Laryngeal Squamous Cell Carcinoma: A Single-center Retrospective Study. Medicine (Baltimore). 2016 Feb;95(6):e2689. doi: 10.1097/MD.0000000000002689. PubMed PMID: 26871799; PubMed Central PMCID: PMC4753894.

8. Wang L, Li H, Yang Z, Guo Z, Zhang Q. Preoperative Serum Thyrotropin to Thyroglobulin Ratio Is Effective for Thyroid Nodule Evaluation in Euthyroid Patients. Otolaryngol Head Neck Surg. 2015 Jul;153(1):15-9. doi: 10.1177/0194599815579877. PubMed PMID: 25883100.

9. Wang L, Li H, Yang Z, Chen W, Zhang Q. Outcomes of Primary Squamous Cell Carcinoma of Major Salivary Glands Treated by Surgery With or Without Postoperative Radiotherapy. J Oral Maxillofac Surg. 2015 Sep;73(9):1860-4. doi: 10.1016/j.joms.2015.03.016. PubMed PMID: 25865716.

10. Fan SF, Zeng ZY, Peng HW, Guo ZM, Wang SL, Zhang Q. Sentinel lymph node biopsy versus elective neck dissection in patients with cT1-2N0 oral tongue squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Feb;117(2):186-90. doi: 10.1016/j.oooo.2013.09.012. PubMed PMID: 24332157.

11. Chen SW, Zhang Q#, Yang AK, Li Z, Zhong Y, Li H, Zeng Y, Zhuang SM, Wang LP, Song LB, Guo ZM, Song M. Overexpression and cytoplasmic localization of Sam68 correlate with tumour progression and poor prognosis in patients with clinically N0 oral tongue cancer. Head Neck Oncol. 2012 Sep 9;4(2):61. PubMed PMID: 23104543.

12. Chen YF, Zhang WD, Wu MW, Ou-Yang D, Zhang Q. Inflammatory myofibroblastic tumor of the head and neck. Med Oncol. 2011 Dec;28 Suppl 1:S349-53. doi: 10.1007/s12032-010-9729-3. PubMed PMID: 21042957.

13. Liu XK, Zhang Q#, Li Q, Liu WW, Li H, Zeng ZY, Guo ZM. Laryngeal framework reconstruction using titanium mesh in glottic cancer after frontolateral vertical partial laryngectomy. Laryngoscope. 2010 Nov;120(11):2197-202. doi: 10.1002/lary.21103. PubMed PMID: 20824791.

Updated May 2020 by International Office, Sun Yat-sen University Cancer Center

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