Patient Care
    Zeng Mu-Sheng
    Title Professor and Vice-President
    Profile

    Prof. Musheng Zeng is a vice director and professor of Sun Yat-sen University Cancer Center. He gained his Ph.D. degree at Sun Yat-sen University in 1998 and had his Post-doc training in Tennessee State University and New England Medical Center, Tufts University from 1999 to 2003. Prof. Musheng Zeng moved back to China to start his lab since 2003. In 2014, he was awarded as Changjiang Scholar Professor from Ministry of Education of China.

    Zeng’s laboratory majorly engages in the pathogenesis and etiology of Nasopharyngeal Carcinoma (NPC), especially the mechanism of EBV infection and transformation in nasopharyngeal epithelial cells. In endemic regions, NPC presents as a complex disease caused by an interaction of Epstein-Barr virus (EBV) chronic infection, environmental, and genetic factors, in a multistep carcinogenic process.

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    Yi-Xin Zeng
    Title Professor and Former President
    Profile

    Dr. Yi-Xin Zeng had been the President of Sun Yat-sen University Cancer Center since 1997 till 2013. He had served as the Director of State Key Laboratory of Oncology in South China since 2004. Now he is a professor and president of Peking Union Medical College. Dr. Zeng obtained his PhD and MD at Sun Yat-sen University of Medical Sciences in 1990. He was elected as member of the Chinese Academy of Science in 2005. He received his post-doc training on molecular mechanisms of cancer pathogenesis in Tokyo Metropolitan Institute of Gerontology, Tokyo University and University of Pennsylvania from 1992 to 1997. He was appointed as a professor of Sun Yat-sen University of Medical Sciences and vice president of Sun Yat-sen University Cancer Center after he returned to China in 1997. He was elected as Outstanding Young Teacher by Ministry of Education in 2002, Outstanding Young Expert by Ministry of Health in 2006.

    His research is devoted to the pathogenesis of cancer and cancer biotherapy, with a focus on nasopharyngeal carcinoma (NPC) and Epstein-Barr virus (EBV), on which he has published over 300 papers in international famous journals including Nature, Nature Genetic and Cancer Research. He has been honored with many awards for his research, including Second Class Award for Natural Science Achievements (National Office for Science and Technology Awards, 2005), He-Liang-He-Li Award for Science and Technology Advancement (2007), Award for Outstanding Science and Technology Achievements in Guangdong Province (the People's Government of Guangdong Province, 2011).

    Currently Dr. Zeng is leading the 863 program (National High Technology Research and Development Program of China) “Molecular Classification and Individualized Therapy for Major Diseases” and 973 program (National Basic Research Program of China) “Research on Mechanisms and Intervene of Oncogenic Virus”.

    He served as the president of International Association of EB Virus and Related Diseases from 2006 to 2008. He is the chief editor of national postgraduate textbook Oncology designed by the Minister of Health, the Editor-in-chief of the Chinese Journal of Cancer and Vice Editor-in-chief of medicine undergraduate textbook Clinical Oncology. He has also acted as the vice president of China Anti-Cancer Association since 2007.

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    Fu Li-wu
    Title Professor and Director
    Profile

    Li-wu Fu, Ph.D., Professor, Doctoral Supervisor. Prof. Fu obtained his PhD in the field of Cancer Pharmacology from the Sun Yat-sen University and carried out his doctoral research in South Carolina Medical University from 1999 to 2001. 

    Prof. Fu’s field of expertise includes anticancer drug pharmacology, molecular mechanism of anticancer drugs and individual cancer chemotherapy. In recent years, he mainly focused on the study of molecular mechanism of anti-cancer drugs, drug resistance of cancer cells (especially multidrug resistance), the innate resistance of cancer stem cells and the individual cancer chemotherapy. For the excellent work in the research of “Strategies for overcoming ABC-transporters-mediated multidrug resistance (MDR) of tumor cells”, Prof. Fu’s team gained the first prize of “Chinese Anti-Cancer Association (CACA) Science and Technology Award” (Ranked first) and the second prize of “Institute of Higher Education Outstanding Scientific Research Achievements Award” (Natural Science Award) in 2011. 

    As the leader of the research group, he has won the provincial and ministerial level scientific and technological awards for several times, including the “Outstanding young scientific and technological talents award from Ministry of Health”, the “Servier outstanding young workers Pharmacology Award” and the “Ding Ying Science Award” in 2011. 

    Prof. Fu has presided over and successfully completed more than 40 key research projects on national, provincial and ministerial scale and horizontal fund projects. 

    More than 200 research papers have been published and up to 100 papers have been published in high-quality SCI journals, including Cancer Res (6 articles), Oncotarget, Mol Med, Cell Cycle, Eur J Cancer, Mol Cancer Ther, Birth J Parmacol, Biochem Pharmacol , Mol Pharmacol etc. and 10 invention patents have been attained.

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    Zhu Xiaofeng
    Title Deputy Director and Professor
    Profile

    Zhu Xiaofeng is the deputy director of the Experimental Research Department and a professor in the State Key Laboratory of Oncology in South China. He is also the Director of the Committee of Cancer pharmacology in Guangdong Pharmacological Society, a Standing member of the Committee of Cancer pharmacology in Chinese Pharmacological Society, aStanding member of the Committee of anticancer drug in Chinese association for cancer research, Editorial board member for Chinese Journal of Cancer; Editorial board member for Frontier in Pharmacology and an Advisory board member for Advances in Therapy. His main research interest is Signal transduction in cancer and targeted anticancer drugs.


    He also is at the origin of 8 patents and products such as Shikonin derivatives and their antitumor effect or Houttuyninum compositions and methods for inhibiting the activity of erbB-2 based thereon and was awarded with numerous grants and honours, for example for Targeted therapy for cancer stem cells., 973 program, 4,500,000yuan RMB, from 2012 to 2016.

     

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    Liu Qiang
    Title Professor and Deputy director
    Profile

    Dr. Qiang Liu is the professor and deputy director of experimental research department of State Key Laboratory of Oncology in South China in Sun Yat-sen University Cancer Center. Dr. Liu received his bachelor's degree from Nanjing University in China in 1989, his Ph.D. from University of Illinois at Urbana-Champaign in 1997, and his M.D. from University of Illinois at Chicago in 2000. He completed his residency training at Mt. Sinai Hospital in New York. In 2004, Dr. Liu served as Principal Investigator on research grants about Aurora-A in cell division from the National National Institutes of Health in Harvard Medical School. 

    He then joined the Sun Yat-sen University Cancer Center as a Professor through “Hundred Talents Program” of Sun Yat-Sen University in June 2005. Dr. Liu was awarded Innovation of Science and Technology Talent of Science and Technology Ministry(PRC, 2014), Innovation Team Leaders of the Education Ministry (PRC, 2013), Outstanding Mid-Aged Expert of the Public Health Ministry (PRC, 2012),Chief Scientist of Major State Basic Research Development Program (973 program, PRC, 2012), The Second Prize of Science of China Anti-Cancer Association (PRC, 2012), Fellow of American Institution of Medical and Biological Engineering (AIMBE, 2012), and Key Program of National Natural Science Funds (PRC, 2011) etc. Dr. Liu has published more than 60 research papers in peer-reviewed journals including Nat Commun (2014), Autophagy (2012), J Clin Oncol (2010, cover story) etc.

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    Song Gao
    Title Professor
    Profile

        Dr. Song Gao is professor of structural biology in SYSUCC. Dr. Gao obtained his Bachelor degree in biotechnology at Wuhan University, 2005. He then went to Europe for graduate study and obtained Master degree in Structural proteomics at University of St Andrews in UK, 2006 and Doctor degree with “Summa Cum Laude” at Max-Delbrück-Centrum for Molecular Medicine (MDC)/Freie Universtät Berlin, Germany, 2011. During his time in Germany, he started to investigate the functional mechanisms of dynamin superfamily. After a short period of postdoc training in MDC, Dr. Gao was granted the National Recruitment Program of Global Youth Experts and moved to SYSUCC to start his own research group in 2012. In SYSUCC, Dr. Gao has established a multi-disciplinary research platform which combines structural biology with single-molecule biophysics, biochemistry and cell biology. Dr. Gao is currently supported by several research grants from the National Natural Science Foundation of China, National Basic Research Program of China, and Natural Science Foundation of Guangdong Province. The research of Dr. Gao’s group is focused on (1) Molecular basis of membrane remodelling mediated by dynamin superfamily, and (2) RNA-manipulating enzymes involved in tumorigenesis and metastasis.

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    Jia Weihua
    Title Professor, PI, and Doctoral Advisor
    Profile

    Prof. Jia has dedicated herself to research in cancer genetics and genomics, and cancer molecular epidemiology. She has extensive experience in the etiology of cancer, especially the gene-environment interaction in nasopharyngeal carcinoma (NPC). Prof. Jia firstly revealed the epidemic pattern of NPC in high incidence area and clarified the NPC incidence trend during two decades. These studies have provided scientific data in high incidence areas of China and offered a scientific basis for national public health decision-making and global cancer statistics. She firstly demonstrated that cigarette smoking may play a role via induction of EBV reactivation in NPC carcinogenesis at both epidemiological level and molecular level. And her team has identified novel susceptibility loci of NPC, lymphoma, and colorectal cancer in recent years. She has identified susceptible genes and core pathways associated with ESCC tumorigenesis and prognosis though next-generation sequencing.  She has published more than 100 papers in peer-previewed scientific journals, including Nat Genet, J Natl Cancer Inst, and Cancer Res, etc. In addition, she made great contributions to the standards formulation of China’s biobank, and also, she devoted to studying the areas of translational research and promoting scholarly communication and exchanges. Her projects won National Natural Science Awards (second prize) in 2005 and 2016, Chinese medical science and technology prizes (first prize) in 2004 and 2015, international natural science award in China (first prize) in 2003 and progress prize in scientific and collective technology in China (first prize) in 2016.

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    Xiaofeng Zheng
    Title Special Professor
    Profile
    Prof. Xiaofeng Zheng is a specially appointed professor at Sun Yat-sen University Cancer Center. Prof. Zheng received his Ph.D. of Biological Chemistry and Molecular Pharmacology at Harvard Medical School, Boston, Massachusetts, USA, in 1993, and his postdoctoral training at Howard Hughes Medical Institute and the Department of Chemistry and Chemical Biology at Harvard University. He is a pioneer in mTOR signaling and an expert in nutrient signaling, cancer growth and metabolism, and targeted therapy. He has been a professor at the Department of Pharmacology and Co-Director of Program in Cancer Pharmacology and Preclinical Therapeutics of Rutgers Cancer Institute of New Jersey. Prof. Zheng has published many papers as first or corresponding author in top peer-reviewed journals including Nature, Cell, PNAS, EMBO, Curr Biol, and Nature Communications.
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    Wang Hui-Yun
    Title Professor, Director of Lab. of Bionomics and Tumor Marker
    Profile
    Dr. Hui-Yun Wang is a professor in Basic Oncology and Director of Laboratory of Bionomics and Tumor Marker, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center. He obtained his Bachelor in Medicine (equivalent to MD in the US) at Hengyang Medical College in 1982, and PhD at Sun Yat-sen University of Medical Sciences (SUMS), China, in 1997, when he was appointed as Vice Director of Department of Tumor Pathology, Cancer Institute, SUMS. In 1990’s, he proposed and implemented the project "Locating and Cloning of Nasopharyngeal Carcinoma Susceptibility Gene", which result was published in Nature Genetics (2002). Then, he got his postdoctoral training at the Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey in 2000 – 2003, and then he was promoted to Adjunct Assistant Professor. During the period, he developed a novel microarray technology consisting of over 1000 multiplex PCR and single-base extension assay, which can genotype SNPs from one single sperm and profile gene expression on one single cell, which was published in Genome Research (2005). In Match 2007, he returned to the Sun Yat-Sen University as a professor of the “Hundred Talent Plan”. Since then, he developed various microarrays, including SNP array, microRNA array, gene array, lncRNA array and protein array. With these microarrays, he explored several kinds of tumors including hepatocellular carcinoma (Clin Cancer Res, 2013) and nasopharyngeal carcinoma (Lancet Oncology, 2012). Dr. Wang has published more than 70 research papers.
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    Guan Xin-Yuan
    Title Professor
    Profile

    Prof. Xin-Yuan Guan got his PhD degree in 1993 at the University of Arizona. After postdoctoral training at the University of Michigan, he was recruited by National Human Genome Research Institute in NIH as a senior staff fellow in 1993. He was then moved to the Department of Clinical Oncology, The University of Hong Kong in 1999 as an Associate Professor, and promoted to Professor in 2007. He is Professor of Sun Yat-sen University Cancer Center since 2007.

    His major scientific contributions include: 

    (1)development and application of Micro-FISH technique in cancer research; 

    (2)identification and characterization of novel oncogenes, such as EIF5A2 and CHD1L in various cancers; and 

    (3)identification and characterization of cancer stem cells in hepatocellular and esophageal carcinomas. 


    Currently, Prof. Guan’s research interests include cancer stem cell, cancer microenvironment, and cancer related genes in liver, esophageal and nasopharyngeal cancers. He has published more than 240 peer-reviewed papers in international journals including in Science, Nature Genetics, Nature Medicine, Cell Stem Cell, J Clin Invest, Gastroenterology, Hepatology, Gut, Cancer Research, and Oncogene.

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    Chen Shuai
    Title Professor
    Profile
    Dr. Chen is professor of oncology and molecular medicine in Sun Yat-sen University Cancer Center. Dr. Chen obtained his Bachelor in Biotechnology at Xiamen University, P.R.China in 2002, and obtained his PhD in Genetics at Fudan University, P.R.China in 2007, respectively. His postdoctoral training at University of Minnesota Masonic Cancer Center and Stony Brook University in New York provided him with great opportunities to explore the fields of tumorigenesis and tumor genetics. He was appointed as Associate Professor at Institute of Microbiology, Chinese Academy of Sciences in March 2011. He then joined the Cancer Research Institute at Sun Yat-sen University Cancer Center (SYSUCC) as a Professor in April 2014. Dr. Chen has published more than 20 research papers.
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    Ran-yi Liu
    Title Professor
    Profile

    Dr. Liu is a professor of oncology and molecular medicine in Sun Yat-sen University Cancer Center. He obtained his Bachelor in Biochemistry at Nanjing University in China in 1989, and Master Degree in Molecular Biology at Tongji Medical University in 1998 and PhD in Oncology at Sun Yat-sen University in 2007, respectively. He then finished postdoctoral training at Indiana University School of Medicine in United States in August 2009. He is a standing member of the Committee of Cancer pharmacology in Guangdong Pharmacological Society since 2014. He has gained 3 research grants from National Natural Science Foundation of China, 1 grant from 863 projects of Ministry of Science & Technology and other 11 grants, and the total budget is over 18 million yuan RMB. He has published more than 60 research papers included in the SCI (Science Citation Index). He received the first prize in Natural Science Award of Ministry of Education and the first prize in Science & Technology Progress Award of Guangdong Province in 2011. His group has developed anti-angiogenic gene medicine in phase III clinical trial.

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    Li Yan
    Title Associate Professor
    Profile
    Dr. Yan Li obtained her M.D. degree at Yunyang Medical College and Ph.D degree at Sun Yat-sen Medical University in 1995 and 2001, respectively. She then joined Sun Yat-sen University Cancer Center (SYSUCC) as Assistant Professor. She went back to the SYSUCC in 2005 after her postdoctoral training at Yale University Cancer Center. She is now an Associate Professor in SYSUCC. Dr. Yan Li has published more than 30 research papers.
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    Na Liu
    Title Associate Professor
    Profile
    Dr. Na Liu is an Associate Professor of Department of Experiment Research. She obtained her M.D. of Oncology at Nan Hua University in 2007 and Ph.D. of Oncology at Sun Yat-sen University in 2009, respectively. She joined the Department of Experiment Research at Sun Yat-sen University Cancer Center (SYSUCC) as an Associate Professor via “One Hundred Talents Project of Sun Yat-sen University” in November 2013. Dr. Liu’s research is focused on the molecular mechanisms of individualized treatment for nasopharyngeal carcinoma and she has published 10 peer-reviewed papers.
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    Li Xiaoxing
    Title Associate Professor
    Profile
    Dr. Xiaoxing Li is an associate professor of State key laboratory of Oncology in South China in Sun Yat-sen University Cancer Center (SYSUCC). Dr. Li obtained his PhD at school of Public Health, Chinese University of Hong Kong (CUHK), Hong Kong, China in 2010. He subsequently became a postdoctoral fellow in Institute of Digestive Disease of CUHK, focusing on researches in molecular basis and clinical implication of epigenetic alteration in gastrointestinal (GI) cancers. He joined the Lab of Cancer Precision Therapy, SYSUCC as an associate professor in Feb 2014. He was involved in several major research projects on epigenetic alteration in GI cancers as Principal Investigator or Co-investigator with more than 20 publications as fist- or co-author in peer reviewed journals including Hepatology, Gut, Cell Research, Oncogene, Cancer.
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    Ke Pan
    Title Associate Professor
    Profile

    Dr. Ke Pan is the associate professor of experiment research department of Sun Yat-sen University Cancer Center. Dr. Pan obtained his Bachelor and PhD at South China Agriculture University, P. R. China in 2000 and 2006, respectively. His doctoral project focused on the immunoassay of toxic compound based on the generating of monoclonal antibody and recombinant single chain Fv. 


    In 2006, he started his postdoctoral training at Sun Yat-sen University Cancer Center, focused on cancer immunotherapy based on Dendritic cells (DC) and T cells. 


    In 2009, he was promoted to be assistant professor at Sun Yat-sen University Cancer Center, continue his study of cancer immunotherapy, including basic and clinical research. 

    In 2014, he was promoted to be associate professor. In the study period at Sun Yat-sen University Cancer Center, he investigated DC function, correlated signal pathway, antigen selection and optimized cytokine cocktails for DC mature in detailed, as well as explored the clinical efficacy of cytokine induced killer cells (CIK) for the cancer patients. 


    In 2014, at the same time, he was appointed to be visiting scientist at University of Texas MD Anderson Cancer Center, focused on the study of function and characters of long term persistence memory T cells target on solid tumor cells. Dr. Pan has published more than 40 research papers.

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    Shijun Wen
    Title Associate Professor
    Profile
    Dr. Shijun Wen is associate professor of medicinal chemistry in Experimental Research Department of Sun Yat-sen University. Dr. Wen obtained his Bachelor in chemistry from Jilin University, and PhD in organic chemistry in 2004 from Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences. During 2005-2010, He worked as a postdoctoral research fellow at Schools of Chemistry and Medicine, Southampton University, and then as a research associate at the Department of Chemistry, University of Cambridge. In November 2010, Dr. Wen joined Sun Yat-sen University Cancer Center as an associate professor working on the anticancer drug development and the synthetic methodology study. Dr. Wen has published more than 20 SCI research papers.
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    Yumin (Christie) Hu
    Title Associate Professor
    Profile
    Dr. Yumin Hu received her M.D. degree from Guangzhou Medical College and obtained Ph.D. and postdoctoral training at The University of Texas, MD Anderson Cancer Center. She won the Rosalie B. Hite Fellowship for Cancer Research for year 2005-2008 for her Ph.D. research project “ROS Stress in Ras-Transformed Cancer Cells: Mechanisms and Therapeutic Implications”. In 2009, she won The Kimberly Patterson Fellowship Award for Leukemia Research for her postdoctoral fellow research projects “Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound -phenylethyl isothiocyanate”. In 2010, Dr. Yumin Hu was recruited to Sun Yat-sen University Cancer Center as Associate Professor and her research area has been focused on Metabolic alterations and redox regulation in cancer cells.
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